A
Alain Gougeon
Researcher at French Institute of Health and Medical Research
Publications - 49
Citations - 7001
Alain Gougeon is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Follicular phase & Ovarian follicle. The author has an hindex of 31, co-authored 49 publications receiving 6583 citations. Previous affiliations of Alain Gougeon include University of Paris.
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Regulation of ovarian follicular development in primates: facts and hypotheses.
TL;DR: A picture has emerged depicting the classic endocrine control of ovarian function by LH and FSH, entangled in a maze of regulatory systems hinging on cell-cell interactions between follicular cells, via action of a variety of molecules.
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Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause
TL;DR: This model shows follicle numbers decline bi-exponentially rather than as a simple exponential function of age, as had been assumed, with a first exponential rate parameter of -0.097 and a second of - 0.237, and predicts the impact of step reductions of follicles numbers on the prospective span of menstrual life was predicted.
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Dynamics of follicular growth in the human: a model from preliminary results
TL;DR: The ovulatory follicle originates from a cohort of pre-antral follicles that have differentiated their theca interna 85 days earlier under the control of the high peri-ovulatory steroid and gonadotrophin levels.
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Age-related changes of the population of human ovarian follicles: increase in the disappearance rate of non-growing and early-growing follicles in aging women.
TL;DR: The view that depletion of the NGF pool is caused mainly by atresia in younger women but mainly by entrance of NGF into the growing pool in older women is supported.
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The antral follicle count: practical recommendations for better standardization.
Frank J.M. Broekmans,Dominique de Ziegler,Colin M. Howles,Alain Gougeon,Geoffrey Trew,François Olivennes +5 more
TL;DR: The use of a standardized approach according to the practical recommendations for antral follicle counting as presented is encouraged in future clinical trials and routine practice.