Showing papers in "Fertility and Sterility in 2010"

TL;DR: The mechanisms responsible for DNA fragmentation in human sperm, including those occurring during spermatogenesis and transport through the reproductive tract are reviewed, and how abnormal sperm could be dealt with by the oocyte and how sperm DNA abnormalities may interfere with normal embryo and fetal development are discussed.

TL;DR: These data suggest that despite major differences in reproductive hormone levels with increasing body weight, only extreme levels of obesity may negatively influence male reproductive potential.

TL;DR: Analysis of the genetic factors that impact male factor infertility will provide valuable insights into the creation of targeted treatments for patients and the determination of the causes of idiopathic infertility.

TL;DR: The comprehensive chromosome screening method described overcomes many of the problems that limited earlier aneuploidy screening techniques and may finally allow preimplantation genetic screening to achieve the benefits predicted by theory.

TL;DR: A biopsy-induced inflammatory response may facilitate the preparation of the endometrium for implantation, and increased MIP-1B expression could possibly serve for prediction of implantation competence.

TL;DR: Female obesity impairs IVF outcome, but embryo quality is not affected, pointing to an alteration in the uterine environment.

TL;DR: The EFI is a simple, robust, and validated clinical tool that predicts PRs after endometriosis surgical staging and provides reassurance to those patients with good prognose and avoids wasted time and treatment for those with poor prognoses.

TL;DR: The prevalence of abnormal results for evidence-based and investigative diagnostic tests did not differ among women with different numbers of pregnancy losses, and Evaluation of all couples with two or more consecutive miscarriages is recommended.

TL;DR: The findings that women with higher vitamin D level in their serum and FF are significantly more likely to achieve CP following IVF-embryo transfer are novel.

TL;DR: The use of a standardized approach according to the practical recommendations for antral follicle counting as presented is encouraged in future clinical trials and routine practice.

TL;DR: Recurrent implantation failure warrants investigation of CE as a contributing factor in patients undergoing IVF-ET who repeatedly failed to conceive despite the transfer of good-quality embryos; however, there were no differences in subsequent clinical pregnancy or ongoing pregnancy rates after successful antibiotic treatment.

TL;DR: The couple with the best chance of pregnancy can be described as follows: an under 30 woman with cervical or anovulatory infertility and a man with a TMS >or=5 million spermatozoa.

TL;DR: Current treatment guidelines should be updated to incorporate findings from recent literature that show that GnRH antagonist protocols consistently reduce OHSS and that Gn RH agonist triggering has considerable promise in preventing OHSS, although further RCTs will be needed to confirm this.

TL;DR: Patients with male factor infertility had significantly increased methylation alteration at six of seven imprinted loci tested, with differences in significance observed between oligozoospermic and abnormal protamine patients, suggesting that risk of transmission of epigenetic alterations may be different with diagnoses.

TL;DR: This study suggests that ovarian reserve could be reduced after laparoscopic cystectomy; however, it could be restored thereafter up to 3 months postoperative in reproductive women.

TL;DR: The AFC and AMH are the most significant predictors of poor response to ovarian stimulation during ART and the AMH and AFC demonstrate a similar predictive power but are not predictive of nonconception, which is dependent on the woman's age.

TL;DR: Cryo singletons have better neonatal outcome than offspring after fresh ET but poorer compared with non-arts, and the adjusted risks of very preterm birth and neonatal admittance were also significantly increased.

TL;DR: The results suggest that vitrification/warming is currently the most efficient means of oocyte cryopreservation in relation to subsequent success in establishing pregnancy.

TL;DR: A small bolus of hCG in the GnR Ha group secured the luteal phase, resulting in a comparable reproductive outcome in the two groups, however, a nonsignificant difference of 7% in delivery rates justifies further studies to refine the use of GnRHa for ovulation induction.

TL;DR: Preliminary pregnancy experience after MRgFUS is encouraging, with a high rate of delivered and ongoing pregnancies, and a high level of pregnancy outcomes and complications.

TL;DR: A SNP microarray-based single cell aneuploidy screening technology has been established and validated and clinical validation studies are underway to determine the predictive value of this methodology.

TL;DR: Hyaluronic acid may optimize ICSI outcome by favoring selection of spermatozoa without DNA fragmentation and with normal nucleus, and may also be used to speed up the selection for sperm selection before intracytoplasmic morphologically selected sperm injection (IMSI).

TL;DR: Ovarian transplantation in humans is a robust procedure, even after cryopreservation, and vitrification might prove to be more effective than slow freezing.

TL;DR: Investigation of cryopreserved ovarian cortex from Danish female patients diagnosed with leukemia was unable to locate leukemic cells in the ovarian cortex; however, PCR detected potentially malignant cells inThe majority of cases.

TL;DR: Long-term cyclic and continuous postoperative use of OCP can effectively reduce and delay endometrioma recurrence.

TL;DR: Simultaneous oocyte vitrification increases the success of assisted reproductive technology in poor-prognosis patients and avoids the consequences of the short lifespan of the transplanted tissue.

TL;DR: A randomized clinical trial demonstrated that FSH/IUI treatment was of no added value and the time it took to establish a pregnancy that led to a live birth and cost-effectiveness.

TL;DR: The combined technique (stripping and ablation) has proved not to be deleterious to the ovary and was possible in all cases.

TL;DR: Oocyte cryopreservation appears to be a viable option for fertility preservation in some centers and was not statistically different from cycles performed consecutively in age-matched controls using fresh, nonfrozen autologous or donor oocytes during a similar time period.

TL;DR: It is found that anxiety existed at higher levels than depression, anxiety was underdiagnosed, and more women with PCOS who reported infertility were depressed.