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Alain Vanderkelen
Researcher at Vrije Universiteit Brussel
Publications - 26
Citations - 1403
Alain Vanderkelen is an academic researcher from Vrije Universiteit Brussel. The author has contributed to research in topics: Transplantation & Pseudomonas aeruginosa. The author has an hindex of 17, co-authored 26 publications receiving 1308 citations.
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Journal ArticleDOI
Direct detection and identification of Pseudomonas aeruginosa in clinical samples such as skin biopsy specimens and expectorations by multiplex PCR based on two outer membrane lipoprotein genes, oprI and oprL.
Danièle De Vos,Antonio Jr. Lim,Jean-Paul Pirnay,Marc Struelens,Christian Vandenvelde,Luc Duinslaeger,Alain Vanderkelen,Pierre Cornelis +7 more
TL;DR: A multiplex PCR assay based on the simultaneous amplification of two lipoprotein genes, oprI and oprL, appears promising for the rapid and sensitive detection of P. aeruginosa in clinical specimens.
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Molecular Epidemiology of Pseudomonas aeruginosa Colonization in a Burn Unit: Persistence of a Multidrug-Resistant Clone and a Silver Sulfadiazine-Resistant Clone
Jean-Paul Pirnay,Danièle De Vos,Christel Cochez,Florence Bilocq,Jean Pirson,Marc Struelens,Luc Duinslaeger,Pierre Cornelis,Martin Zizi,Alain Vanderkelen +9 more
TL;DR: Cross-acquisition, resulting from insufficient compliance with infection control measures, was the major route of colonization in a 32-bed burn wound center, and all predominant strains except the SSDr strain belonged to recently identified clonal complexes.
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Pseudomonas aeruginosa displays an epidemic population structure
Jean-Paul Pirnay,Danièle De Vos,Christel Cochez,Florence Bilocq,Alain Vanderkelen,Martin Zizi,Bart Ghysels,Pierre Cornelis +7 more
TL;DR: An epidemic population structure for P. aeruginosa is suggested, comparable with that of Neisseria meningitidis, a superficially clonal structure with frequent recombinations, in which occasionally highly successful epidemic clones arise.
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Analysis of the Pseudomonas aeruginosa oprD gene from clinical and environmental isolates.
Jean-Paul Pirnay,Danièle De Vos,Dimitris Mossialos,Alain Vanderkelen,Pierre Cornelis,Martin Zizi +5 more
TL;DR: The wide mutational diversity of clinical as well as environmental isolates, compared with the laboratory strain(s), is highlighted through the systematic genetic analysis of a chromosomal porin gene (oprD) in relation to a specific antibiotic resistance in Pseudomonas aeruginosa.
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High frequency percussive ventilation and conventional ventilation after smoke inhalation: a randomised study.
TL;DR: It is suggested that HFPV can improve blood oxygenation during the acute phase following inhalation injury allowing reduction of FiO(2).