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Alba Sánchez-Fernández
Researcher at Autonomous University of Barcelona
Publications - 6
Citations - 126
Alba Sánchez-Fernández is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Inflammation & Experimental autoimmune encephalomyelitis. The author has an hindex of 3, co-authored 4 publications receiving 42 citations.
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Journal ArticleDOI
OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
TL;DR: It is found that EAE mice fed an OLT1177-enriched diet prophylactically were significantly protected against functional deficits and demyelination in the spinal cord, and first data suggest that OLT 1177 could have clinical benefit for the treatment of MS in humans.
Journal ArticleDOI
IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8
Alba Sánchez-Fernández,Stephanie Zandee,Jesús Amo-Aparicio,Marc Charabati,Alexandre Prat,Cecilia Garlanda,Elan Z. Eisenmesser,Charles A. Dinarello,Charles A. Dinarello,Rubèn López-Vales +9 more
TL;DR: It is demonstrated that IL-37 reduces inflammation and protects against neurological deficits and myelin loss in EAE mice by acting via IL1-R5/IL1- R8, and that this protective physiological mechanism is defective in MS individuals.
Journal ArticleDOI
Neuroinflammation Quantification for Spinal Cord Injury.
TL;DR: Evidence indicates that the inflammatory response that occurs in the spinal cord following injury contributes importantly to spread tissue damage to healthy regions adjacent to the lesion site, and consequently, to increase neurological deficits.
Journal ArticleDOI
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis
Alba Sánchez-Fernández,Stephanie Zandee,Mauricio Mastrogiovanni,Marc Charabati,Homero Rubbo,Alexandre Prat,Rubèn López-Vales +6 more
TL;DR: In this article , the effects of specialized pro-resolving mediators (SPMs) on the severity of multiple sclerosis (MS) were investigated in mice with experimental encephalomyelitis (EAE).
Journal ArticleDOI
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis
Alba Sánchez-Fernández,Stephanie Zandee,Mauricio Mastrogiovanni,Marc Charabati,Homero Rubbo,Alexandre Prat,Rubèn López-Vales +6 more
TL;DR: In this article , the effects of specialized pro-resolving mediators (SPMs) on the severity of multiple sclerosis (MS) were investigated in mice with experimental encephalomyelitis (EAE).