A
Alberto Bertotto
Researcher at University of Perugia
Publications - 68
Citations - 1590
Alberto Bertotto is an academic researcher from University of Perugia. The author has contributed to research in topics: Antigen & T lymphocyte. The author has an hindex of 25, co-authored 68 publications receiving 1557 citations.
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Journal ArticleDOI
Lymphocytes bearing the γδ T cell receptor in acute Brucella melitensis infection.
Alberto Bertotto,Roberto Gerli,Fabrizio Spinozzi,C Muscat,F Scalise,G. Castellucci,M Sposito,F Candio,R. Vaccaro +8 more
TL;DR: Further studies are needed to determine whether the selective expansion of the γδ T cell subpopulation observed during the clinical course of the infection is driven by antigenic determinant(s) borne by the pathogen in vivo or is due to host‐derived stimuli, such as autologous heat‐shock proteins expressed on the surface of the infected cells.
Journal ArticleDOI
Human breast milk T lymphocytes display the phenotype and functional characteristics of memory T cells.
Alberto Bertotto,Roberto Gerli,Giulio Fabietti,S. Crupi,Carla Arcangeli,Francesco Scalise,R. Vaccaro +6 more
TL;DR: In this paper, the authors found that milk T lymphocytes are almost exclusively composed of the one which exhibits the CD45Rlow, CDw29, UCHL1, LFA-1 high memory T cell phenotype.
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Long-term immunologic effects of thymectomy in patients with myasthenia gravis.
Roberto Gerli,Roberto Paganelli,Andrea Cossarizza,C Muscat,Giovanni Piccolo,Daniela Barbieri,Stefano Mariotti,Daniela Monti,Onelia Bistoni,Elda Raiola,Franco Maria Venanzi,Alberto Bertotto,Claudio Franceschi +12 more
TL;DR: In this article, the authors evaluated long-term immunologic effects of therapeutic thymectomy in patients with myasthenia gravis (MG) and found that the association between MG and laboratory findings of systemic autoimmune disease may be in part related to Tx rather than to MG.
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Increased Allergen-Specific, Steroid-Sensitive γδ T Cells in Bronchoalveolar Lavage Fluid from Patients with Asthma
Fabrizio Spinozzi,E. Agea,Onelia Bistoni,Nicolino Forenza,Alessandro Monaco,Gabrio Bassotti,Ildo Nicoletti,Carlo Riccardi,Fausto Grignani,Alberto Bertotto +9 more
TL;DR: Interestingly, the in vivo and in vitro studies provide evidence that apoptosis is the basic mechanism through which corticosteroid treatment acts on this T-lymphocyte type, thereby confirming the results of previous investigations.
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High levels of the soluble form of CD30 molecule in rheumatoid arthritis (RA) are expression of CD30+ T cell involvement in the inflamed joints.
Roberto Gerli,C Muscat,Onelia Bistoni,Brunangelo Falini,C Tomassini,E. Agea,Rita Tognellini,P Biagini,Alberto Bertotto +8 more
TL;DR: Data from this study strongly support an involvement of CD30+ T cells in the immune processes of rheumatoid synovitis, and may suggest a relationship between Th2‐type cytokine‐secreting T cells and the pathological response in RA.