A
Alberto Redaelli
Researcher at Polytechnic University of Milan
Publications - 368
Citations - 10259
Alberto Redaelli is an academic researcher from Polytechnic University of Milan. The author has contributed to research in topics: Mitral valve & Aortic valve. The author has an hindex of 51, co-authored 340 publications receiving 8871 citations. Previous affiliations of Alberto Redaelli include State University of New York System & Instituto Politécnico Nacional.
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Hierarchical structure and nanomechanics of collagen microfibrils from the atomistic scale up.
TL;DR: An experimentally validated model of the nanomechanics of a collagen microfibril that incorporates the full biochemical details of the amino acid sequence of constituting molecules and the nanoscale molecular arrangement is presented, enabling the bottom-up elucidation of structure-property relationships in a broader class of collagen materials.
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Fluid–structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm
TL;DR: The complex mechanical interaction between blood flow and wall dynamics in a three dimensional custom model of a patient AAA was studied by means of computational coupled fluid-structure interaction analysis, providing a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions.
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Molecular and Nanostructural Mechanisms of Deformation, Strength and Toughness of Spider Silk Fibrils.
TL;DR: This model develops the first spider silk mesoscale model, bridging the scales from Angstroms to tens to potentially hundreds of nanometers, and demonstrates that the specific nanoscale combination of a crystalline phase and a semiamorphous matrix is crucial to achieve the unique properties of silks.
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Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues
Anna Marsano,Chiara Conficconi,Chiara Conficconi,Marta Lemme,Marta Lemme,Paola Occhetta,Emanuele Gaudiello,Emiliano Votta,Giulia Cerino,Alberto Redaelli,Marco Rasponi +10 more
TL;DR: The proposed heart-on-a-chip device represents a relevant step forward in the field, providing a standard functional three-dimensional cardiac model to possibly predict signs of hypertrophic changes in cardiac phenotype by mechanical and biochemical co-stimulation.
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Possible role of decorin glycosaminoglycans in fibril to fibril force transfer in relative mature tendons—a computational study from molecular to microstructural level
Alberto Redaelli,Simone Vesentini,Monica Soncini,Pasquale Vena,Sara Mantero,Franco Maria Montevecchi +5 more
TL;DR: The ability of decorin GAGs to transfer forces between adjacent fibrils is investigated and the length of the fibril is likely to play the major role in determining stiffness in mature tendons.