A
Alejandro Bravo-Cuellar
Researcher at Mexican Social Security Institute
Publications - 96
Citations - 1360
Alejandro Bravo-Cuellar is an academic researcher from Mexican Social Security Institute. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 19, co-authored 88 publications receiving 1151 citations. Previous affiliations of Alejandro Bravo-Cuellar include University of Guadalajara & University of Paris.
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Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions
Trinidad García-Iglesias,Alicia del Toro-Arreola,Benibelks Albarran-Somoza,Susana del Toro-Arreola,Pedro Ernesto Sánchez-Hernández,María Guadalupe Ramírez-Dueñas,Luz Ma Adriana Balderas-Peña,Alejandro Bravo-Cuellar,Pablo C Ortiz-Lazareno,Adrian Daneri-Navarro +9 more
TL;DR: It is reported here for the first time that NK cell-activating receptors NKp30 and NKp46 are significantly down-regulated in cervical cancer and high grade squamous intraepithelial lesion (HGSIL) patients.
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Augmented serum level of major histocompatibility complex class I-related chain A (MICA) protein and reduced NKG2D expression on NK and T cells in patients with cervical cancer and precursor lesions.
Naela Arreygue-Garcia,Adrian Daneri-Navarro,Alicia del Toro-Arreola,Angel Cid-Arregui,Oscar Gonzalez-Ramella,Luis Felipe Jave-Suárez,Adriana Aguilar-Lemarroy,Rogelio Troyo-Sanromán,Alejandro Bravo-Cuellar,Vidal Delgado-Rizo,Trinidad García-Iglesias,Georgina Hernández-Flores,Susana del Toro-Arreola +12 more
TL;DR: High sMICA levels are found in sera from patients with both cervical cancer and precursor lesions when compared with healthy donors and a diminution in the number of NKG2D-expressing NK and T cells in the patient samples is observed.
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Oxidative stress in macrophages from spleen of Nile tilapia (Oreochromis niloticus) exposed to sublethal concentration of endosulfan
Martha Cecilia Tellez-Bañuelos,Anne Santerre,Josefina Casas-Solís,Alejandro Bravo-Cuellar,Galina Zaitseva +4 more
TL;DR: It can be concluded that short exposure to low concentration of endosulfan stimulated macrophage activity but that there was no significant reduction in the structural parameters of the IIR.
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Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence
Georgina Hernández-Flores,Pablo C Ortiz-Lazareno,José Manuel Lerma-Díaz,Jorge R. Dominguez-Rodriguez,Luis Felipe Jave-Suárez,Adriana Aguilar-Lemarroy,Ruth de Celis-Carrillo,Susana del Toro-Arreola,Yessica C Castellanos-Esparza,Alejandro Bravo-Cuellar,Alejandro Bravo-Cuellar +10 more
TL;DR: In vitro whether PTX alone or in combination with CIS induces apoptosis and/or senescence in cervix cancer HeLa and SiHa cell lines infected with HPV types 16 and 18, as well as in immortalized keratinocytyes HaCaT cells is studied.
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MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor‐κB and activator protein‐1
Pablo C Ortiz-Lazareno,Georgina Hernández-Flores,Jorge R. Dominguez-Rodriguez,José Manuel Lerma-Díaz,Luis Felipe Jave-Suárez,Adriana Aguilar-Lemarroy,Piedad C. Gomez-Contreras,Daniel Scott-Algara,Alejandro Bravo-Cuellar,Alejandro Bravo-Cuellar +9 more
TL;DR: In this study, the human monocyte cell line U937 stimulated with lipopolysaccharide and phorbol 12‐myristate 13‐acetate as a model is used to investigate the in vitro effects of MG132, a proteasome inhibitor, on the release of proinflammatory cytokines and their receptors and on the expression of their membrane and soluble receptors.