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Aleksandra Grzelakowska
Researcher at Lodz University of Technology
Publications - 18
Citations - 131
Aleksandra Grzelakowska is an academic researcher from Lodz University of Technology. The author has contributed to research in topics: Fluorescence & Chemistry. The author has an hindex of 5, co-authored 16 publications receiving 48 citations.
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Journal ArticleDOI
Selective, stoichiometric and fast-response fluorescent probe based on 7-nitrobenz-2-oxa-1,3-diazole fluorophore for hypochlorous acid detection
Małgorzata Świerczyńska,Daniel Słowiński,Aleksandra Grzelakowska,Marcin Szala,Jaroslaw Romanski,Karolina Pierzchała,Przemysław Siarkiewicz,Radosław Michalski,Radosław Podsiadły +8 more
TL;DR: In this paper, a new selective probe containing the thiomorpholine unit (TM) was synthesized and examined for the fluorescence-based detection of hypochlorous acid (HOCl).
Journal ArticleDOI
Characterization of the reactivity of luciferin boronate - A probe for inflammatory oxidants with improved stability
Marcin Szala,Aleksandra Grzelakowska,Julia Modrzejewska,Przemysław Siarkiewicz,Daniel Słowiński,Małgorzata Świerczyńska,Jacek Zielonka,Radosław Podsiadły +7 more
TL;DR: The synthesis and characterization of luciferin boronic acid pinacol ester (LBE) is reported, showing potential as an improved probe for the detection of inflammatory oxidants in biological settings, with improved stability and response time.
Journal ArticleDOI
Two-photon fluorescent probe for cellular peroxynitrite: Fluorescence detection, imaging, and identification of peroxynitrite-specific products.
Aleksandra Grzelakowska,Monika Zielonka,Karolina Dębowska,Julia Modrzejewska,Marcin Szala,Adam Sikora,Jacek Zielonka,Radosław Podsiadły +7 more
TL;DR: In this article, a naphthalene-based boronate probe, NAB-BE, was used for the detection of inflammatory oxidants, including peroxynitrite, hypochlorous acid, and hydrogen peroxide.
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Recent progress in the synthesis of firefly luciferin derivatives
Radosław Podsiadły,Aleksandra Grzelakowska,Julia Modrzejewska,Przemysław Siarkiewicz,Daniel Słowiński,Marcin Szala,Małgorzata Świerczyńska +6 more
TL;DR: Over the last decade, by using different methods, a lot of analogues of luciferin/aminoluciferin have been synthesized, and therefore, in this review, the recent progress in the design and synthesis of synthetic luciferins is summarized in a manner that all readers can be inspired to use, and/or design, and or develop the useful far red/NIR bioluminescent substrates for luciferase.
Journal ArticleDOI
On the chemical reactivity of tricyanofuran(TCF)-based near-infrared fluorescent redox probes – Effects of glutathione on the probe response and product fluorescence
Przemysław Siarkiewicz,Radosław Michalski,Adam Sikora,Renata Smulik-Izydorczyk,Marcin Szala,Aleksandra Grzelakowska,Julia Modrzejewska,Asha Bailey,Jacek E. Nycz,Balaraman Kalyanaraman,Jan Grzegorz Małecki,Jacek Zielonka,Radosław Podsiadły +12 more
TL;DR: The results reported with TCF-based probes may be affected by the changes in intracellular glutathione, in addition to the desired analyte, so a modified probe derived from 1-naphthalene boronic acid is reported, which has similar reactivity toward peroxynitrite.