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Alex Bajamonde
Researcher at Genentech
Publications - 6
Citations - 11792
Alex Bajamonde is an academic researcher from Genentech. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 5, co-authored 6 publications receiving 11100 citations.
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Journal ArticleDOI
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2
Dennis J. Slamon,Brian Leyland-Jones,Steven Shak,Hank Fuchs,Virginia E. Paton,Alex Bajamonde,Thomas Fleming,Wolfgang Eiermann,Janet M. Wolter,Mark D. Pegram,José Baselga,Larry Norton +11 more
TL;DR: The addition of trastuzumab to chemotherapy was associated with a longer time to disease progression, a higher rate of objective response, a longer duration of response, and a lower rate of death at 1 year.
Journal ArticleDOI
The VIVA Trial Vascular Endothelial Growth Factor in Ischemia for Vascular Angiogenesis
Timothy D. Henry,Brian H. Annex,George R. McKendall,Michael Azrin,John J. Lopez,Frank J. Giordano,Prediman K. Shah,James T. Willerson,Raymond L. Benza,Daniel S. Berman,C. Michael Gibson,Alex Bajamonde,Amy Chen Rundle,J. T. Fine,Edward R. McCluskey +14 more
TL;DR: The VIVA (Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis) trial as discussed by the authors was designed to evaluate the safety and efficacy of intracoronary and intravenous infusions of rhVEGF.
Journal ArticleDOI
Determination of HER2 gene amplification by fluorescence in situ hybridization and concordance with the clinical trials immunohistochemical assay in women with metastatic breast cancer evaluated for treatment with trastuzumab.
Noel Dybdal,Grazyna Leiberman,Steven M. Anderson,Bryan McCune,Alex Bajamonde,Robert L. Cohen,Robert D. Mass,Corsee Sanders,Michael F. Press +8 more
TL;DR: Her2 status determined by CTA-IHC and FISH are significantly correlated; however, differences between these two assays can a ect patient selection for trastuzumab therapy.
Journal ArticleDOI
Targeted Therapy: Wave of the Future
TL;DR: Understanding Gene Alterations in Human Breast Cancer Gene alterations play an important role in the origin and pathogenesis of human breast cancer and are hypothesized to occur by an accumulated series of genetic and phenotypic changes in pathways regulating cell growth.
Journal Article
The treatment of metastatic renal cell carcinoma patients with recombinant human gamma interferon
Eric J. Small,Geoffrey R. Weiss,Umme K. Malik,Philip J. Walther,David H. Johnson,George Wilding,Timothy M. Kuzel,Alex Bajamonde,Virginia E. Paton +8 more
TL;DR: Recombinant interferon gamma 1b has only minimal efficacy in the treatment of metastatic renal cell carcinoma, and Pretreatment variables associated with increased survival were male sex, higher Karnofsky performance status, higher hemoglobin, and low LDH.