A
Alex Dugrillon
Researcher at Heidelberg University
Publications - 6
Citations - 539
Alex Dugrillon is an academic researcher from Heidelberg University. The author has contributed to research in topics: Gene & Messenger RNA. The author has an hindex of 6, co-authored 6 publications receiving 524 citations.
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Autologous concentrated platelet-rich plasma (cPRP) for local application in bone regeneration
TL;DR: An autologous procedure to prepare a high concentrate from platelet-rich plasma (cPRP) for clinical application in bone regeneration is presented and a 17-fold increase in platelet concentrations was achieved compared to the patients' whole bloods and platelet counts correlated with increased levels of TGF-beta1 within the cPRP.
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Messenger RNA profiling of human platelets by microarray hybridization
TL;DR: A mRNA profile of human platelets is provided and it is demonstrated that nucleated cells were not detectable by applying a genomic PCR approach with 50 amplification cycles and any leukocyte contamination of platelet preparations can lead to false results.
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Microarray-based genotyping for blood groups: comparison of gene array and 5'-nuclease assay techniques with human platelet antigen as a model.
Peter Bugert,Simon McBride,Graham Smith,Alex Dugrillon,Harald Klüter,Willem H. Ouwehand,Paul Metcalfe +6 more
TL;DR: Most blood group alloantigens specific for red cells and platelets (PLTs) are based on single‐nucleotide polymorphisms (SNPs) in genes encoding relevant membrane proteins.
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Flow cytometric analysis of T cell proliferation in a mixed lymphocyte reaction with dendritic cells
Xuan Duc Nguyen,Hermann Eichler,Alex Dugrillon,Christoph Piechaczek,Michael Braun,Harald Klüter +5 more
TL;DR: Flow cytometric analysis permits simple, precise and rapid quantification of T cell proliferation in a mixed lymphocyte reaction with DCs so that specific T cell subsets involved in antigen-specific proliferation can be evaluated in detail.
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A novel method for simultaneous analysis of specific platelet antibodies: SASPA.
TL;DR: Improved method based on simultaneous detection of various platelet‐specific immunoglobulin G (IgG) and IgM antibodies that proved to be a rapid and reliable assay that required less platelets than other methods.