Showing papers in "Transfusion in 2005"

TL;DR: The literature was systematically reviewed to determine whether a prolonged prothrombin time or elevated international normalized ratio predicts bleeding during invasive diagnostic procedures.

TL;DR: Estimates for human immunodeficiency virus (HIV)‐1 and hepatitis C virus (HCV) transfusion‐transmitted risks have relied on incidence derived from repeat donor histories and imprecise estimates for infectious, preseroconversion window periods (WPs).

TL;DR: AMD3100, a selective antagonist of CXCR4, rapidly mobilizes CD34+ hematopoietic progenitor cells from marrow to peripheral blood with minimal side effects.

TL;DR: The shortage of human blood and organs has led to increased interest in animal substitutes, and a major xenoantigen in pigs is linear B, a cross-reactive, B-like antigen expressed on red blood cells and other tissues that is recognized by naturally occurring antibodies present in human serum.

TL;DR: A meta‐analysis was performed to summarize the results of different research studies about tranexamic acid infusion in reducing postoperative blood loss and the number of transfused red cells (RBC) units.

TL;DR: An understanding of the correlates of donation intentions among nondonors could facilitate targeting psychological prerequisites of donation decisions in recruitment campaigns.

TL;DR: Data is obtained on the incidence of postoperative infection in patients undergoing elective orthopedic surgery and receiving white blood cell‐filtered blood components prepared according to current standards.

TL;DR: It is important to characterize viral dynamics in early hepatitis C virus (HCV) infection to further the understanding of viral pathogenesis and the potential for secondary transmission in acute infection through blood transfusion or other routes.

TL;DR: Recombinant factor VIIa (rF‐VIIa) is being increasingly used as rescue therapy in such cases as well as in clinical practice, but little information is available on its safety and efficacy for this indication.

TL;DR: The feasibility of the use of large‐scale DNA analysis in a microarray as a substitute for blood group typing was determined.

TL;DR: A photochemical treatment process with amotosalen‐HCl and long‐wavelength ultraviolet light (UVA), which cross‐links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentrates.

TL;DR: Transfusion recipients who become alloimmunized to red cell or platelet (PLT) antigens require antigen‐negative blood to limit adverse transfusion reactions, and blood collection facilities use regulated and unregulated antibodies to phenotype blood, which can be prohibitive depending on the antisera and demand.

TL;DR: A better understanding of Canadian blood donor beliefs and motivations is needed to develop targeted interventions and recruiters must know how motivation variables and correlation patterns differ with donor experience and sex.

TL;DR: Evaluation of alloanti‐D formation in a D– female patient after transfusion of apparently D– blood from an Austrian donor led to discovery of a so far unknown DEL type.

TL;DR: RHD blood group alleles with reduced or absent antigen expression are a clinically significant and heterogeneous group and should be considered a clinical indication for further studies.

TL;DR: The efficacy of apheresis PLTs treated with riboflavin plus ultraviolet (UV) light was investigated in a single‐blind, crossover study in comparison to untreated PLTs.

TL;DR: A large number of patients in sub‐Saharan Africa are infected with hepatitis B surface antigen or hepatitis C virus antibodies, and the percentage of screened blood is limited to approximately 75% for human immunodeficiency virus antibodies (anti‐HIV), 50% for liver surface antigen, and 19% for hepatitis Cirus antibodies.

TL;DR: A large number of patients with hereditary angioedema have experienced abdominal edema attacks associated with vomiting and diarrhea, and these attacks have a high potential for causing recurrent disability of the patient.

TL;DR: To assess the value of antenatal screening to detect neonatal alloimmune thrombocytopenia due to anti‐HPA‐1a, a prospective study was carried out to quantify the potential clinical benefits and determine whether screening would be cost‐effective.

TL;DR: In this paper, a multiplex polymerase chain reaction was developed to both amplify and fluorescently label 19 gene fragments of red cell (RBC) and platelet (PLT) antigens in one reaction.

TL;DR: This study was performed to explore the usage of BNP in the differential diagnosis of TACO, where BNP is a 32‐amino‐acid polypeptide secreted from the cardiac ventricles in response to ventricular volume expansion and pressure overload.

TL;DR: A retrospective evaluation of the currently applied bacteriologic screening program for platelet concentrates contaminated with Bacillus cereus prompted by two cases of life‐threatening sepsis reported to the regional hemovigilance office.

TL;DR: A randomized, controlled, double‐blind, Phase III trial (SPRINT) evaluated hemostatic efficacy and safety of PCT apheresis PLTs compared to untreated conventional apheresIS PLTs in 645 thrombocytopenic oncology patients requiring PLT transfusion support.

TL;DR: This data indicates that routine quality control testing for bacterial contamination in apheresis platelet products was implemented in all 36 regional blood centers of the American Red Cross in March 2004 and showed positive results.

TL;DR: From the Transfusion Medicine Unit, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center and Strong Memorial Hospital, Rochester, New York.

TL;DR: This multicenter, randomized, controlled, double‐blind Phase’III clinical study evaluated the therapeutic efficacy and safety of apheresis platelets photochemically treated with amotosalen and ultraviolet’A light compared with conventional apheresIS PLTs.

TL;DR: The D antigen includes category D, partial D, and weak D types, which are important because anti‐D alloimmunization can occur in some but not all persons that express a variant RHD allele.

TL;DR: This study examines the effect of the wash step as well as that of PT storage on various quality control variables of UCB units.

TL;DR: This work has shown that Del individuals retain a grossly intact RHD gene or have a portion of RHD in their genomes, and no Del phenotype has yet been shown to induce a primary or secondary alloanti‐D immunization.

TL;DR: Two new strategies are being developed to reduce the risk of pathogen transmission associated with platelet (PLT) transfusion and one of these strategies involves using nanofiltration technology.