Alex Michotte

TL;DR: It is found that there is no clear advantage of diffusion-weighted echo-planar imaging in the evaluation of tumor extension and the contrast between gliomas, metastases, meningioma, and white matter was generally lower on diffusion- Weighted images and ADC maps compared with conventional MR imaging.

TL;DR: No correlation could be established between VEGFR2, PDGFR-α, and KIT gene copy numbers or protein expression and the effects of sunitinib, and single-agent sunit inib at 37.5 mg/day had insufficient activity to warrant further investigation of this monotherapy regimen in recurrent HGG.

TL;DR: Functional imaging may improve the noninvasive diagnosis of pseudoprogression, but randomized prospective studies are needed to evaluate the real impact of pseudiprogression and validate neuroradiological techniques able to make a reliable distinction between tumor recurrence and pseudopregression.

TL;DR: The authors present a systematic review of bright lesions on diffusion-weighted MR images and their differential diagnosis, with emphasis on the practical and clinical approaches of differential diagnosis.

TL;DR: The hypothesis that alterations in transport of glutamate, and more particular via GLT-1, may be involved in AD pathogenesis is supported.