C
Cristo Chaskis
Researcher at Vrije Universiteit Brussel
Publications - 28
Citations - 1277
Cristo Chaskis is an academic researcher from Vrije Universiteit Brussel. The author has contributed to research in topics: Glioma & Temozolomide. The author has an hindex of 14, co-authored 28 publications receiving 1199 citations. Previous affiliations of Cristo Chaskis include Erasmus Hospital & Université libre de Bruxelles.
Papers
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Journal Article
Diffusion-weighted MR imaging of intracerebral masses: comparison with conventional MR imaging and histologic findings.
Tadeusz Stadnik,Cristo Chaskis,Alex Michotte,Wael Shabana,Katrijn L Van Rompaey,Robert Luypaert,Lubos Budinsky,Vladimir Jellus,Michel Osteaux +8 more
TL;DR: It is found that there is no clear advantage of diffusion-weighted echo-planar imaging in the evaluation of tumor extension and the contrast between gliomas, metastases, meningioma, and white matter was generally lower on diffusion- Weighted images and ADC maps compared with conventional MR imaging.
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Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma
Bart Neyns,Jan Sadones,Eric Joosens,F. Bouttens,L. Verbeke,Jean-François Baurain,Lionel D'Hondt,Theo Strauven,Cristo Chaskis,P. In't Veld,Alex Michotte,J. De Greve +11 more
TL;DR: Cetuximab was well tolerated but had limited activity in this patient population with progressive HGG and a minority of patients may derive a more durable benefit but were not prospectively identified by EGFR gene copy number.
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Phase II study of sunitinib malate in patients with recurrent high-grade glioma
Bart Neyns,Jan Sadones,Cristo Chaskis,Martine Dujardin,Hendrik Everaert,S. Lv,Johnny Duerinck,Olli Tynninen,Nina N. Nupponen,Alex Michotte,J. De Greve +10 more
TL;DR: No correlation could be established between VEGFR2, PDGFR-α, and KIT gene copy numbers or protein expression and the effects of sunitinib, and single-agent sunit inib at 37.5 mg/day had insufficient activity to warrant further investigation of this monotherapy regimen in recurrent HGG.
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Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.
TL;DR: Functional imaging may improve the noninvasive diagnosis of pseudoprogression, but randomized prospective studies are needed to evaluate the real impact of pseudiprogression and validate neuroradiological techniques able to make a reliable distinction between tumor recurrence and pseudopregression.
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Morphological quantitative analysis of intracranial pressure waves in normal pressure hydrocephalus
Christian Raftopoulos,Cristo Chaskis,Florence Delecluse,Francis Cantraine,Luc Bidaut,Jacques Brotchi +5 more
TL;DR: An extended quantitative classification of intracranial pressure waves is proposed that can be used alone to determine which patients should undergo a shunting procedure and which one should the most improve.