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Alexander M. Shneider
Researcher at Ariel University
Publications - 45
Citations - 963
Alexander M. Shneider is an academic researcher from Ariel University. The author has contributed to research in topics: Immunogenicity & Cancer. The author has an hindex of 18, co-authored 41 publications receiving 790 citations. Previous affiliations of Alexander M. Shneider include Saint Petersburg State Polytechnic University & Russian Academy of Sciences.
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Can melatonin reduce the severity of COVID-19 pandemic?
TL;DR: By using the safe over-the-counter drug melatonin, this work may be immediately able to prevent the development of severe disease symptoms in coronavirus patients, reduce the severity of their symptoms, and/or reduce the immuno-pathology of coronav virus infection on patients’ health after the active phase of the infection is over.
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Four stages of a scientific discipline; four types of scientist.
TL;DR: The classification of the evolutionary stages that a scientific discipline evolves through and the type of scientists that are the most productive at each stage is proposed and might be instrumental for society in organizing and managing the scientific process.
Journal Article
Activation of the aryl hydrocarbon receptor/transcription factor and bone marrow stromal cell-dependent preB cell apoptosis.
Koichi Yamaguchi,Richard I. Near,Raymond A. Matulka,Alexander M. Shneider,Paul Toselli,Anthony F. Trombino,David H. Sherr +6 more
TL;DR: A murine model of B cell development was created to support the hypothesis that the AhR effects immunosuppression by inducing stromal cells to deliver a death signal to lymphocytes and underscore the regulatory role played by bone marrow stroma cells in lymphopoiesis.
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Immunization with influenza A NP-expressing vaccinia virus recombinant protects mice against experimental infection with human and avian influenza viruses.
Anatoly D. Altstein,A. K. Gitelman,Yu. A. Smirnov,L. M. Piskareva,Ludmila Zakharova,G. V. Pashvykina,Maxim M. Shmarov,Oleg P. Zhirnov,N. P. Varich,Petr O. Ilyinskii,Alexander M. Shneider +10 more
TL;DR: In order to try to increase immune system presentation of NP-protein-derived peptides, and thereby increase their immunogenicity, a vaccinia-based NP-expressing recombinant containing a rapid proteolysis signal covalently bound to the NP protein was constructed.
Journal ArticleDOI
Induction of PreB cell apoptosis by 7,12-dimethylbenz[a]anthracene in long-term primary murine bone marrow cultures.
Koichi Yamaguchi,Raymond A. Matulka,Alexander M. Shneider,Paul Toselli,Anthony F. Trombino,Shi Yang,Laurie J. Hafer,Koren K. Mann,Xiao-Jing Tao,Jonathan L. Tilly,Richard I. Near,David H. Sherr +11 more
TL;DR: The results implicate programmed cell death as a mechanism underlying DMBA-mediated immunosuppression and suggest that preB cell death is influenced by local interactions with AhR+ bone marrow stromal cells.