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Alexander Nivorozhkin
Researcher at Southern Federal University
Publications - 44
Citations - 2212
Alexander Nivorozhkin is an academic researcher from Southern Federal University. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Tautomer. The author has an hindex of 14, co-authored 44 publications receiving 2048 citations. Previous affiliations of Alexander Nivorozhkin include Centre national de la recherche scientifique & Stanford University.
Papers
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Journal ArticleDOI
Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol
TL;DR: A critical overview of the effects of XO inhibitors in various pathophysiological conditions is presented and the various emerging therapeutic strategies offered by this approach are reviewed.
Journal ArticleDOI
Ligand environment and the structure of schiff base adducts and tetracoordinated metal-chelates
TL;DR: Tetracoordinated metal-chelate complexes with six-membered metallocycles as discussed by the authors have been shown to be stable in the presence of tautomeric forms of the ligands.
Journal ArticleDOI
Enzyme-Activated Gd3+ Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement
Alexander Nivorozhkin,Andrew Kolodziej,Peter Caravan,Matthew T. Greenfield,Randall B. Lauffer,Thomas J. McMurry +5 more
TL;DR: Clinically relevant relaxivity enhancement of a magnetic resonance imaging (MRI) contrast agent has been achieved by using prodrug Gd3+ complexes using lysine residues from the prodrug to expose a group that has a high affinity to human serum albumin and promotes enhanced relaxivity, thus enabling the detection of targets at submicromolar concentrations.
Patent
Peptide-based multimeric targeted contrast agents
Zhaoda Zhang,Peter Caravan,Thomas J. McMurry,Andrew Kolodziej,Nair Shrikumar,John C. Amedio,Stephane Dumas,Xifang Wang,Wei-Chuan Sun,Alexander Nivorozhkin,Steffi K. Koerner +10 more
TL;DR: In this paper, peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents, and methods of combining peptide and contrast agents.
Patent
Isoquinoline derivatives and methods of use thereof
Prakash Jagtap,Erkan Baloglu,Duzer John H Van,Csaba Szabo,Andrew L. Salzman,Aloka Roy,William Williams,Alexander Nivorozhkin +7 more
TL;DR: In this paper, the authors describe a class of Isoquinoline derivatives and their compositions and methods of making and using the compounds, as well as methods of using them in pharmaceutical applications.