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Alfonso Colombatti

Researcher at University of Udine

Publications -  247
Citations -  10838

Alfonso Colombatti is an academic researcher from University of Udine. The author has contributed to research in topics: Extracellular matrix & Tumor microenvironment. The author has an hindex of 55, co-authored 245 publications receiving 9947 citations. Previous affiliations of Alfonso Colombatti include University of Parma & National Institutes of Health.

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Long non-coding RNAs and cancer: a new frontier of translational research?

TL;DR: This review focuses on long non-coding RNAs that are involved in cancer and describes some of the functions of lncRNAs and the possible genetic mechanisms that underlie lncRNA expression changes in cancer, as well as current and potential future applications of lNCRNA research in the treatment of cancer.
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The inflammatory chemokine CCL5 and cancer progression.

TL;DR: This review summarizes updated information on the role of CCL5 and its receptor CCR5 in cancer cell proliferation, metastasis, and the formation of an immunosuppressive microenvironment and highlights the development of newer therapeutic strategies.
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p27Kip1-stathmin interaction influences sarcoma cell migration and invasion

TL;DR: A functional link between proliferation and invasion of tumor cells is provided based on diverse activities of p27 kip1 in different subcellular compartments and high stathmin and low cytoplasmic p27kip1 expression correlate with the metastatic phenotype of human sarcomas in vivo.
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Structural and functional features of the alpha 3 chain indicate a bridging role for chicken collagen VI in connective tissues.

TL;DR: The type I collagen-binding and the cell-attachment properties of the alpha 3(VI) chain provide direct information for the role of type VI collagen in connective tissues.
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Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding.

TL;DR: A novel antitumoral effect could, at least partially, explain the very low recurrence rates found in a large pilot study using TARGIT and open a novel avenue for identifying new molecular targets and testing novel therapeutic agents.