A
Alfredo García-Layana
Researcher at University of Navarra
Publications - 129
Citations - 3989
Alfredo García-Layana is an academic researcher from University of Navarra. The author has contributed to research in topics: Macular degeneration & Choroidal neovascularization. The author has an hindex of 27, co-authored 118 publications receiving 3096 citations. Previous affiliations of Alfredo García-Layana include Carlos III Health Institute.
Papers
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Journal ArticleDOI
Diagnostic accuracy of retinal abnormalities in predicting disease activity in MS
Jorge Sepulcre,Manuel Murie-Fernandez,Angel Salinas-Alamán,Alfredo García-Layana,Bartolomé Bejarano,Pablo Villoslada +5 more
TL;DR: Retinal nerve fiber layer atrophy and the presence of retinal periphlebitis are associated with disease activity, suggesting that retinal evaluation can be used as biomarkers of multiple sclerosis activity.
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Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
Matthew C. Pickering,Elena Goicoechea de Jorge,Rubén Martínez-Barricarte,Sergio Recalde,Alfredo García-Layana,Kirsten L. Rose,Jill Moss,Mark Walport,H. Terence Cook,Santiago Rodríguez de Córdoba,Marina Botto +10 more
TL;DR: These animals represent the first model of aHUS and provide in vivo evidence that effective plasma C3 regulation and the defective control of complement activation on renal endothelium are the critical events in the molecular pathogenesis of FH-associated aH US.
Journal Article
Retinal Thickness Study with Optical Coherence Tomography in Patients with Diabetes
Hortensia Sánchez-Tocino,Aurora Alvarez-Vidal,Miguel J. Maldonado,Javier Moreno-Montañés,Alfredo García-Layana +4 more
TL;DR: It is suggested that foveal thickening over 180 microm measured by OCT may be useful for the early detection of macular thickening and may be an indicator for a closer follow-up of the patient with diabetes.
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Optical coherence tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism.
Miguel J. Maldonado,Lilian Ruiz-Oblitas,Juan M Munuera,Daniel Aliseda,Alfredo García-Layana,Javier Moreno-Montañés +5 more
TL;DR: Corneal microstructure by optical coherence tomography after laser in situ keratomileusis (LASIK) for high myopia with and without astigmatism appears to be a useful tool for the evaluation of both the qualitative and quantitative anatomic outcome of LASIK.
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Myopic maculopathy: Current status and proposal for a new classification and grading system (ATN)
Jorge Ruiz-Medrano,Javier A. Montero,Ignacio Flores-Moreno,Luis Arias,Alfredo García-Layana,José M. Ruiz-Moreno +5 more
TL;DR: A more comprehensive classification system is needed to improve the understanding of the genetic origins of this disease, which is clearly relevant given the interchangeable-but erroneous-use of the terms high and pathologic myopia in genetic research.