Ali Rahman

TL;DR: The pathogenesis of progressive small airway fibrosis characteristic of OB may be inflammatory damage, followed by an aberrant repair process due to excessive TGF-beta production following allograft injury, which suggests modulation of T GF-beta levels or function by antagonists may represent an important approach to control OB.

TL;DR: An alternative technique that preserves the shape of the left atrium and leaves the right atrium intact and improved atrial function in group A may play a part in the prevention of right sided failure following cardiac transplantation.

TL;DR: The difference in the mean ejection fraction in the first week after transplantation suggests that bicaval orthotopic cardiac implantation is associated with a lower right atrial pressure, a lower likelihood of atrial tachyarrhythmias, less need for pacing, less mitral incompetence, less diuretic dose, and a shorter hospital stay.

TL;DR: The bicaval technique maintains good left ventricular function, lower incidence and severity of tricuspid valve dysfunction, and improved survival compared with the standard technique.

TL;DR: Various factors contribute to TR after OHT, the prevalence of which might be lowered by adopting the bicaval technique, early treatment of rejection, and reduction of the number of biopsies performed.