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Alicia A. Cassidy

Researcher at Université de Moncton

Publications -  6
Citations -  99

Alicia A. Cassidy is an academic researcher from Université de Moncton. The author has contributed to research in topics: Protein degradation & Protein metabolism. The author has an hindex of 4, co-authored 6 publications receiving 53 citations. Previous affiliations of Alicia A. Cassidy include Fisheries and Oceans Canada.

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Diel cycling hypoxia enhances hypoxia-tolerance in rainbow trout (Oncorhynchus mykiss): evidence of physiological and metabolic plasticity

TL;DR: Hypoxia tolerance is a plastic trait in fish, and a putatively sensitive species can remodel its physiology and metabolism to effectively cope with diel cycling hypoxia.
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Adjustments of Protein Metabolism in Fasting Arctic Charr, Salvelinus alpinus.

TL;DR: This study is the first to measure both KS and the enzymatic activity of protein degradation in the same fish, allowing us to examine the apparent contribution of different protein degradation pathways to protein turnover in various tissues.
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Protein synthesis is lowered by 4EBP1 and eIF2-α signaling while protein degradation may be maintained in fasting, hypoxic Amazonian cichlids Astronotus ocellatus.

TL;DR: It was determined for the first time in fish that a decrease in protein synthesis during hypoxia is likely controlled by signaling molecules (4EBP1 and eIF2-α, and not simply due to a lack of ATP), and regulated by cell signaling pathways.
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Effects of fasting and refeeding on protein and glucose metabolism in arctic charr.

TL;DR: It is shown that miRNAs (miR-29a and miR-223) could be involved in fish glycogen homeostasis during the early stages of refeeding, which provides a deeper understanding of the molecular mechanisms regulating growth in fish.
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Activation of oxygen-responsive pathways are associated with altered protein metabolism in Arctic char exposed to hypoxia

TL;DR: It is shown that protein metabolism in Arctic char is altered in a tissue-specific fashion during graded hypoxia, which is in accordance with the responses of the three major Hypoxia-sensitive pathways (HIF, UPR and mTOR).