Showing papers by "Alicja Wolk published in 1992"
TL;DR: One of the first to evaluate the incidence of cancer in a population-based cohort of alcoholics of both sexes, the results of this study are consistent with smaller previous studies, which were usually limited to cancer mortality and of short follow-up.
Abstract: The incidence of cancer was studied in a population-based cohort of 9,353 individuals (8,340 men and 1,013 women) with a discharge diagnosis of alcoholism in 1965-83, followed up for 19 years (mean 77) After exclusion of cancers in the first year of follow-up, 491 cancers were observed cf 3432 expected through 1984 (standardized incidence ratio [SIR] = 14, 95 percent confidence interval [CI] = 13-16) A similar excess risk of cancer was seen among men (SIR = 14, CI = 13-16) and among women (SIR = 15, CI = 11-20) We observed the established associations with cancers of the oral cavity and pharynx (SIR = 41, CI = 29-57), esophagus (SIR = 68, CI = 45-99), larynx (SIR = 33, CI = 17-60), and lung (SIR = 21, CI = 17-26), although confounding by smoking likely increased these risk estimates While there was evidence of increased risk for pancreatic cancer (SIR = 15, CI = 09-23), alcoholism did not elevate the incidence of cancer of the stomach (SIR = 09, CI = 6-14), large bowel (SIR = 11, CI = 08-15), prostate (SIR = 10, CI = 08-13), urinary bladder (SIR = 10, CI = 06-15), or of malignant melanoma (SIR = 09, CI = 03-19) Among women, the number of breast cancers observed was close to expected (SIR = 12, CI = 06-22), although a significant excess number of cervical cancers occurred (SIR = 42, CI = 15-91)(ABSTRACT TRUNCATED AT 250 WORDS)
151 citations