A
Aline Lira Xavier
Researcher at Federal University of Paraíba
Publications - 15
Citations - 410
Aline Lira Xavier is an academic researcher from Federal University of Paraíba. The author has contributed to research in topics: Acute toxicity & Toxicity. The author has an hindex of 9, co-authored 15 publications receiving 336 citations.
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Antitumor activity of monoterpenes found in essential oils.
Marianna Vieira Sobral,Aline Lira Xavier,Tamires Cardoso Lima,Damião Pergentino de Sousa,Damião Pergentino de Sousa +4 more
TL;DR: In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed and chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.
Journal ArticleDOI
The controvertible role of kava (Piper methysticum G. Foster) an anxiolytic herb, on toxic hepatitis
Maria de Fatima Duques de Amorim,Margareth de Fátima Formiga Melo Diniz,Maria Salete Trigueiro de Araújo,João Carlos Lima Rodrigues Pita,Jadson Gomes Dantas,Josué do Amaral Ramalho,Aline Lira Xavier,Thayse V. Palomaro,Nelson L. B. Júnior +8 more
TL;DR: The incidence of kava toxicity on the liver remains to be investigated; however, some concerns before or during kava use are important, due to the possibility of severe liver dysfunction.
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Constituintes químicos, avaliação das atividades citotóxica e antioxidante de Mimosa paraibana Barneby (Mimosaceae)
Xirley Pereira Nunes,Xirley Pereira Nunes,Rafael F. Mesquita,Davi A. Silva,Daysianne Pereira de Lira,Vicente Carlos de Oliveira Costa,Marianna Vieira B. Silva,Aline Lira Xavier,Margareth de Fátima Formiga Melo Diniz,Maria de Fátima Agra +9 more
TL;DR: In this article, a phytochemical study of Mimosa paraibana Barneby led to the isolation of its chemical constituents, through the usual chromatographic methods, and further structural identification, using 1H and 13C NMR spectroscopic methods based on one and two-dimensional techniques.
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In Vitro and in Vivo Antitumor Effect of Trachylobane-360, a Diterpene from Xylopia langsdorffiana
João Carlos Lima Rodrigues Pita,Aline Lira Xavier,Tatyanna Kelvia Gomes de Sousa,Vivianne Mendes Mangueira,Josean Fechine Tavares,Robson José de Oliveira Júnior,Robson Cavalcante Veras,Hilzeth de Luna Freire Pessôa,Marcelo Sobral da Silva,Sandra Morelli,Veridiana de Melo Rodrigues Ávila,Teresinha Gonçalves da Silva,Margareth de Fátima Formiga Melo Diniz,Marianna Vieira S. Castello-Branco +13 more
TL;DR: The in vitro and in vivo antitumor effects of trachylobane-360, as well as its cytotoxicity in mouse erythrocytes, reinforce the anticancer potential of this natural diterpene.
Journal ArticleDOI
Toxicity and antitumor potential of Mesosphaerum sidifolium (Lamiaceae) oil and fenchone, its major component
Thaísa Leite Rolim,Déborah R.P. Meireles,Tatianne Mota Batista,Tatyanna Kelvia Gomes de Sousa,Vivianne Mendes Mangueira,Renata Albuquerque de Abrantes,João Carlos Lima Rodrigues Pita,Aline Lira Xavier,Vicente Carlos de Oliveira Costa,Leônia Maria Batista,Marcelo Sobral da Silva,Marianna Vieira Sobral +11 more
TL;DR: EOM caused in vivo cell growth inhibition on Ehrlich ascites carcinoma model by inducing cell cycle arrest, without major changes in the toxicity parameters evaluated.