Antitumor activity of monoterpenes found in essential oils.
Marianna Vieira Sobral,Aline Lira Xavier,Tamires Cardoso Lima,Damião Pergentino de Sousa,Damião Pergentino de Sousa +4 more
TLDR
In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed and chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.Abstract:
Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.read more
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Composition 构好图，出好片
TL;DR: The Oleo-gum-resin exuded by this tree has been regarded as a sovereign remedy in ancient medicine and has marked antiseptic properties.
Book ChapterDOI
Therapeutic and Medicinal Uses of Terpenes
TL;DR: This chapter summarizes the various terpenes, their sources, medicinal properties, mechanism of action, and the recent studies that are underway for designing terpene as a lead molecule in the modern medicine.
Journal ArticleDOI
Terpenes from Forests and Human Health.
TL;DR: The studies that show the biological effectiveness of terpenes support the benefits of forest bathing and propose a potential use of Terpene-containing plant oil as chemotherapeutic agents for treating various human diseases.
Journal ArticleDOI
Linalool bioactive properties and potential applicability in drug delivery systems.
TL;DR: The present review focuses on the anti-inflammatory, anticancer, anti-hyperlipidemic, antimicrobial, antinoceptive, analgesic, anxiolytic, antidepressive and neuroprotective properties of linalool.
Journal ArticleDOI
Synergistic and Additive Effect of Oregano Essential Oil and Biological Silver Nanoparticles against Multidrug-Resistant Bacterial Strains.
Sara Scandorieiro,Larissa Ciappina De Camargo,César Armando Contreras Lancheros,Sueli Fumie Yamada-Ogatta,Celso Vataru Nakamura,Admilton Gonçalves de Oliveira,Célia Guadalupe Tardeli de Jesus Andrade,Nelson Durán,Gerson Nakazato,Renata Katsuko Takayama Kobayashi +9 more
TL;DR: This study describes for the first time the synergistic and additive interaction between OEO and bio-AgNP produced by F. oxysporum against multidrug-resistant bacteria, such as MRSA, and β-lactamase- and carbapenemase-producing Escherichia coli and Acinetobacter baumannii strains.
References
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Journal ArticleDOI
Hallmarks of cancer: the next generation.
TL;DR: Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
Composition 构好图，出好片
TL;DR: The Oleo-gum-resin exuded by this tree has been regarded as a sovereign remedy in ancient medicine and has marked antiseptic properties.
Journal Article
The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L.
TL;DR: TQ and DIM, which are cytotoxic for several types of human tumor cells, may be MDR substrates, and that radical generation may not be critical to their cytotoxicity activity.
Journal ArticleDOI
Targeting Nuclear Factor-κB Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis
TL;DR: The results indicate that the anticancer and antiinflammatory activities previously assigned to TQ may be mediated in part through the suppression of the NF-κB activation pathway, and thus may have potential in treatment of myeloid leukemia and other cancers.