A
Alison Street
Researcher at Alfred Hospital
Publications - 75
Citations - 3918
Alison Street is an academic researcher from Alfred Hospital. The author has contributed to research in topics: Haemophilia & Haemophilia A. The author has an hindex of 26, co-authored 74 publications receiving 3594 citations. Previous affiliations of Alison Street include Monash University & Monash University, Clayton campus.
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Journal ArticleDOI
Guidelines for the management of hemophilia.
A. Srivastava,A. K. Brewer,Evelien P. Mauser-Bunschoten,Nigel S. Key,Steve Kitchen,Adolfo Llinás,C. A. Ludlam,Johnny Mahlangu,K. Mulder,M.-C. Poon,Alison Street +10 more
TL;DR: These evidence‐based guidelines offer practical recommendations on the diagnosis and general management of hemophilia, as well as the management of complications including musculoskeletal issues, inhibitors, and transfusion‐transmitted infections.
Journal ArticleDOI
A revised model of platelet aggregation
Suhasini Kulkarni,Sacha M Dopheide,Cindy L. Yap,Catherine Ravanat,Monique Freund,Pierre Mangin,Kathryn A Heel,Kathryn A Heel,Alison Street,Ian S. Harper,François Lanza,Shaun P. Jackson +11 more
TL;DR: An important role for platelet vWf in initiating the platelet aggregation process under flow is demonstrated and the currently accepted view that the vWF-GPIbalpha interaction is exclusively involved in initiating platelet aggregating at elevated shear rates is challenged.
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Consensus guidelines for warfarin therapy. Recommendations from the Australasian Society of Thrombosis and Haemostasis.
TL;DR: The anticoagulant effect of warfarin should be kept at an international normalised ratio of about 2.5 (desirable range, 2.0‐3.0), although a higher level may be better in a few clinical conditions, as the risk of bleeding increases exponentially with INR and becomes clinically unacceptable once the INR exceeds 5.0.
Journal ArticleDOI
The definition of massive transfusion in trauma: a critical variable in examining evidence for resuscitation.
TL;DR: There seems to be an increase in mortality with fresh frozen plasma:PRBC ratio of 1 : 1 ratio compared with a 1 : 2 ratio, which further excludes patients who die early.
Journal ArticleDOI
Fresh frozen plasma (FFP) use during massive blood transfusion in trauma resuscitation
Biswadev Mitra,Biswadev Mitra,Alfredo Mori,Peter Cameron,Peter Cameron,Mark Fitzgerald,Eldho Paul,Alison Street +7 more
TL;DR: Increased initial survival in association with higher FFP:PRBC ratios during massive transfusion in a population with a high proportion of blunt injuries is shown, although the association is difficult to interpret because of an inherent survival bias.