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Alister Hart

Researcher at Royal National Orthopaedic Hospital

Publications -  283
Citations -  7092

Alister Hart is an academic researcher from Royal National Orthopaedic Hospital. The author has contributed to research in topics: Medicine & Hip resurfacing. The author has an hindex of 41, co-authored 267 publications receiving 6121 citations. Previous affiliations of Alister Hart include Leicester Royal Infirmary & University of Cambridge.

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Metal-on-metal bearings: THE EVIDENCE SO FAR

TL;DR: In this article, a review examines the literature and contemporary presentations on current clinical dilemmas in metal-on-metal hip replacement and concludes that the use of large metal on-metal bearings in hip replacements can result in catastrophic soft-tissue reactions resulting in implant failure and associated complications.
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Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement

TL;DR: Blood metal ions had good discriminant ability to separate failed from well-functioning hip replacements, and the MHRA cut-off level of 7 ppb provides a specific test but has poor sensitivity.
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Systematic review: predicting and optimising response to anti-TNF therapy in Crohn's disease - algorithm for practical management.

TL;DR: Nonresponse and loss of response to anti‐TNF therapies in Crohn's disease represent significant clinical problems for which clear management guidelines are lacking.
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The painful metal-on-metal hip resurfacing

TL;DR: Metal artefact-reduction MRI, three-dimensional CT measurement of the position of the component and inductively-coupled plasma mass spectrometry analysis of cobalt and chromium levels in whole blood on 26 patients with unexplained pain following metal-on-metal resurfacing arthroplasty are carried out.