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Allan M. Maxam
Researcher at Harvard University
Publications - 18
Citations - 21525
Allan M. Maxam is an academic researcher from Harvard University. The author has contributed to research in topics: Gene & RNA. The author has an hindex of 15, co-authored 18 publications receiving 21367 citations.
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Book ChapterDOI
Sequencing end-labeled DNA with base-specific chemical cleavages.
Allan M. Maxam,Walter Gilbert +1 more
TL;DR: The chapter presents techniques for producing discrete DNA fragments, end-labeling DNA, segregating end- labeled fragments, extracting DNA from gels, and the protocols for partially cleaving it at specific bases using the chemical reactions.
Journal ArticleDOI
A new method for sequencing DNA
Allan M. Maxam,Walter Gilbert +1 more
TL;DR: Reactions that cleave DNA preferentially at guanines, at adenines,At cytosines and thymines equally, and at cytosine alone are described.
Journal ArticleDOI
Mapping adenines, guanines, and pyrimidines in RNA
TL;DR: The positions of adenines, guanines, and pyrimidines can be determined by partial nuclease digestion of a terminally labeles RNA molecule and form the basis of an RNA sequencing method and are demonstrated on yeast 5.8S ribosomal RNA.
Journal ArticleDOI
The Nucleotide Sequence of the lac Operator
Walter Gilbert,Allan M. Maxam +1 more
TL;DR: The sequence of RNA transcription copies of this fragment is determined and the sequence has 2-fold symmetry regions; the two longest are separated by one turn of the DNA double helix.
Journal ArticleDOI
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain
TL;DR: The sequence confirms that the variable region gene lies on the DNA separated from the constant region of a mouse immunoglobulin light chain, the VlambdaII gene, andHypervariable region codons appear in the germ-line sequence.