A
Allen J. Bailey
Researcher at University of Bristol
Publications - 97
Citations - 8981
Allen J. Bailey is an academic researcher from University of Bristol. The author has contributed to research in topics: Glycation & Bone remodeling. The author has an hindex of 52, co-authored 97 publications receiving 8600 citations.
Papers
More filters
Journal ArticleDOI
Mechanisms of maturation and ageing of collagen
TL;DR: An understanding of these mechanisms is now leading to the development of inhibitors of glycation and compounds capable of cleaving the cross-links, thus alleviating the devastating effects of ageing.
Journal ArticleDOI
Collagen cross-links in mineralizing tissues: A review of their chemistry, function, and clinical relevance
Lynda Knott,Allen J. Bailey +1 more
TL;DR: The potential for further study into the biochemistry of bone collagen cross-links to provide more subtle information into the mechanisms and etiology of disease and aging of mineralizing tissues is demonstrated.
Journal ArticleDOI
Molecular mechanisms of ageing in connective tissues
TL;DR: The outward manifestations of tissue ageing occurring in the elderly primarily involve the two major structural proteins of the body, collagen and elastin, and the molecular mechanisms involved are gradually being unravelled and will lead to the development of inhibitors of these deleterious effects of ageing.
Journal ArticleDOI
Changes in metabolism of collagen in genitourinary prolapse
TL;DR: It is found that genitourinary prolapse is associated with a reduction in total collagen content and a decrease in collagen solubility, and development of agents to inhibit collagenolytic activity may help in the treatment of this condition.
Journal ArticleDOI
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes
R.G. Paul,Allen J. Bailey +1 more
TL;DR: The nature of these glycation cross-links is now being unravelled and this knowledge is crucial in any attempt to inhibit these deleterious glycation reactions.