Allison Ponzio

TL;DR: Robertson et al. as mentioned in this paper used neuromelanin-sensitive magnetic resonance imaging to visualize and measure locus coeruleus (LC) signal intensity in healthy younger and older adults and found that LC signal intensity was significantly higher in older than younger adults and significantly lower in women than in men.

TL;DR: High arousal enables young people to better detect salient stimuli and in older people, arousal leads to increased processing of all stimuli, which can be explained by age-related changes in how the locus coeruleus–noradrenaline system interacts with cortical attention networks.

TL;DR: It is found that, across younger and older adults, greater LC‐MRI contrast was negatively associated with HF‐HRV during fear conditioning and spatial detection tasks, indicating that individual differences in LC structure relate to key cardiovascular parameters.

TL;DR: The root-mean-square of successive R-R-interval differences (RMSSD) from ECG recordings was used as time-domain measure of HF HRV as discussed by the authors.

TL;DR: The root-mean-square of successive R-R-interval differences (RMSSD) from ECG recordings was used as time-domain measure of HF HRV as mentioned in this paper.