A
Alzbeta Godarova
Researcher at Massachusetts Institute of Technology
Publications - 2
Citations - 491
Alzbeta Godarova is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Gene & Insertional mutagenesis. The author has an hindex of 1, co-authored 1 publications receiving 452 citations.
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Journal ArticleDOI
Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens
Jan E. Carette,Carla P. Guimaraes,Malini Varadarajan,Annie S. Park,Irene Wuethrich,Alzbeta Godarova,Maciej Kotecki,Brent H. Cochran,Eric Spooner,Hidde L. Ploegh,Thijn R. Brummelkamp +10 more
TL;DR: Using insertional mutagenesis to develop a screening method to generate null alleles in a human cell line haploid for all chromosomes except chromosome 8, host factors essential for infection with influenza and genes encoding important elements of the biosynthetic pathway of diphthamide, which are required for the cytotoxic effects ofdiphtheria toxin and exotoxin A are identified.
Posted ContentDOI
An atlas of gene regulatory networks for memory CD4+ T cells in youth and old age
Joseph A. Wayman,Alyssa L. Thomas,Anthony Bejjani,Alexander Katko,Maha Almanan,Alzbeta Godarova,S. A. Korinfskaya,Tareian Cazares,Masashi Yukawa,Leah C. Kottyan,Artem Barski,Claire A. Chougnet,David A. Hildeman,Emily R. Miraldi +13 more
TL;DR: In this paper , the authors integrated single-cell (sc)RNA-seq, scATAC-seq and genome-scale modeling to characterize T follicular helper-like cells (Tfh10) and the full CD4+ memory T cell (CD4+TM) compartment.