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Amaravadhi Harikishore
Researcher at Nanyang Technological University
Publications - 32
Citations - 970
Amaravadhi Harikishore is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: ATP synthase & Medicine. The author has an hindex of 12, co-authored 26 publications receiving 834 citations.
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Correction: Corrigendum: Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells
Seonghoon Kim,Hye Guk Ryu,Juhyun Lee,Joon Shin,Amaravadhi Harikishore,Hoe-Yune Jung,Ye Seul Kim,Ha-Na Lyu,Eun-Ji Oh,Nam-In Baek,Kwan-Yong Choi,Ho Sup Yoon,Kyong-Tai Kim +12 more
TL;DR: In this paper, the authors found that ursolic acid (UA) inhibits the catalytic activity of vaccine-related kinase 1 via direct binding to the protein domain of VRK1.
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Immunophilins: Structures, Mechanisms and Ligands
TL;DR: This review focuses on molecular characteristics of the canonical and non-canonical immunophilin family members from human and Plasmodium falciparum and P. vivax, recent progress on immunophILin inhibitor development, and future perspectives of structure-based design of non-immunosuppressive immunophile ligands with potential pharmacological activities against infectious diseases.
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Luteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1.
Ye Seul Kim,Seong Hoon Kim,Joon Shin,Amaravadhi Harikishore,Jong Kwan Lim,Youngseob Jung,Ha Na Lyu,Nam-In Baek,Kwan Yong Choi,Ho Sup Yoon,Kyong-Tai Kim +10 more
TL;DR: This study suggests that luteolin-induced VRK1 inhibition may contribute to establish a novel cell cycle-targeted strategy for anti-cancer therapy.
Journal ArticleDOI
Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells
Seong Hoon Kim,Hye Guk Ryu,Juhyun Lee,Joon Shin,Amaravadhi Harikishore,Hoe-Yune Jung,Ye Seul Kim,Ha-Na Lyu,Eun-Ji Oh,Nam-In Baek,Kwan-Yong Choi,Ho Sup Yoon,Ho Sup Yoon,Kyong-Tai Kim +13 more
TL;DR: In this article, the authors found that ursolic acid (UA) inhibits the catalytic activity of vaccine-related kinase 1 via direct binding to the protein domain of VRK1.
Journal ArticleDOI
Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent
Amaravadhi Harikishore,Makhtar Niang,Makhtar Niang,Sreekanth Rajan,Peter R. Preiser,Ho Sup Yoon +5 more
TL;DR: The experimental results verify that this novel compound (D44) modulate the PPIase activity of Plasmodium FKBP35 and demonstrate the stage-specific growth inhibition of PlAsmodium falciparum strains.