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Amelia Bartholomew
Researcher at University of Illinois at Chicago
Publications - 63
Citations - 6573
Amelia Bartholomew is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Mesenchymal stem cell & Transplantation. The author has an hindex of 28, co-authored 61 publications receiving 6241 citations. Previous affiliations of Amelia Bartholomew include University of Toronto & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo.
Amelia Bartholomew,Cord Sturgeon,Mandy Siatskas,Karen Ferrer,Kevin R. Mcintosh,Sheila Patil,Wayne Hardy,S. Devine,David S. Ucker,Robert J. Deans,Annemarie Moseley,Ronald Hoffman +11 more
TL;DR: Baboon MSCs have been observed to alter lymphocyte reactivity to allogeneic target cells and tissues, which may prove useful in future applications of tissue regeneration and stem cell engineering.
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Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates
TL;DR: It is suggested that MSCs initially distribute broadly following systemic infusion and later may participate in ongoing cellular turnover and replacement in a wide variety of tissues.
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IFN‐γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
David Polchert,Justin Sobinsky,G. W. Douglas,Martha Kidd,Ada Moadsiri,Eduardo Reina,Kristyn Genrich,Swati Mehrotra,Suman Setty,Brett Smith,Amelia Bartholomew +10 more
TL;DR: It is shown that bone marrow‐isolated MSC can suppress the development of GVHD if given after donor T cell recognition of antigen, and activated MSC could prevent GV HD mortality when given at the time of bone marrow transplantation.
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Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion
Steven M. Devine,Amelia Bartholomew,Nadim Mahmud,Mary Nelson,Sheila Patil,Wayne Hardy,Cord Sturgeon,Terry A. Hewett,Theodore D.K. Chung,Wendy Stock,Dorie Sher,Scott Weissman,Karen Ferrer,Joseph D. Mosca,Robert J. Deans,Annemarie Moseley,Ronald Hoffman +16 more
TL;DR: It is demonstrated that baboon mesenchymal stem cells are not associated with significant toxicity when administered intravenously, are capable of homing to the bone marrow following intravenous infusion, and have the capacity to establish residence within theBone marrow for an extended duration following systemic administration.
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Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance
W. Ge,Jifu Jiang,Miren L. Baroja,J. Arp,Roman Zassoko,W. Liu,W. Liu,Amelia Bartholomew,Bertha Garcia,Hao Wang +9 more
TL;DR: This study supports the clinical applicability of MSCs in transplantation and appears to be instrumental in the induction of allograft‐specific tolerance when administered in combination with a subtherapeutic dose of Rapamycin.