A
Amirali Popat
Researcher at University of Queensland
Publications - 84
Citations - 3965
Amirali Popat is an academic researcher from University of Queensland. The author has contributed to research in topics: Mesoporous silica & Medicine. The author has an hindex of 28, co-authored 66 publications receiving 2742 citations. Previous affiliations of Amirali Popat include Translational Research Institute.
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Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers
TL;DR: A comprehensive summary of the advances made in the last decade and a future outlook on possible applications of MSNs as nanocontainers for storage and delivery of biomolecules and some promising work on enzyme immobilisation using mesoporous silica nanoparticles are highlighted.
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A pH-responsive drug delivery system based on chitosan coated mesoporous silica nanoparticles
TL;DR: In this paper, a core-shell pH-responsive drug-carrier based on chitosan-coated mesoporous silica nanospheres is reported, which is realized by the phosphoramidate covalent bonding between phosphonate groups on the surface of the MSN.
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Resveratrol nanoformulations: Challenges and opportunities
TL;DR: The therapeutic potential of resveratrol is outlined, its mechanisms of action and pharmacokinetic limitations are explored, and potential techniques to improve encapsulation of the drug within nanoparticles, thereby enhancing its clinical potential are highlighted.
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Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery
Karishma T. Mody,Amirali Popat,Donna Mahony,Antonino S. Cavallaro,Chengzhong Yu,Neena Mitter +5 more
TL;DR: An overview on the latest progress on synthesis, adsorption and release kinetics and biocompatibility of MSNs as next generation antigen carriers and adjuvants and insight on fundamental challenges and some future prospects of these nanoparticles as adjuvant are given.
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Enzyme‐Responsive Controlled Release of Covalently Bound Prodrug from Functional Mesoporous Silica Nanospheres
Amirali Popat,Benjamin P. Ross,Jian Liu,Siddharth Jambhrunkar,Freddy Kleitz,Shi-Zhang Qiao,Shi-Zhang Qiao +6 more
TL;DR: Mesoporous silica nanoparticles are functionalized with sulfasalazine, a prodrug of 5-aminosalicylic acid (5-ASA) and sulfapyridine, to generate enzyme-responsive nanocarriers that efficiently released in the presence of the colon-specific enzyme azo-reductase.