Amy L. Filby

TL;DR: The expression responses of a suite of 22 genes involved in reproduction, growth and development in the liver and gonad in adult male and female fathead minnow exposed to the model anti-androgen flutamide and the model synthetic estrogen 17alpha-ethinylestradiol (EE(2) produced distinct expression profiles, suggesting that they largely operate via distinct molecular mechanisms.

TL;DR: These studies show that pre-validation of control genes considering the scope and nature of the experiments to be performed, including both gender and tissue type, is critical for accurate assessments of the effects of environmental estrogens on gene expression in fish.

TL;DR: Overall, dominance resulted in a greater total reproductive success in males but not in females; however, dominant females sired more offspring with the dominant male, and energy invested in dominance behavior appears beneficial for both sexes in zebrafish.

TL;DR: This work applied targeted expression profiling on 40 genes, spanning eight neurological pathways and in four distinct regions of the brain, to screen for regulatory pathways of aggression in the zebrafish, an animal model in which social rank and aggressiveness tightly correlate.

TL;DR: Temporal patterns of expression in the brain of kiss1r, gnrh2, and gnrh3 and a suite of related genes in the hypothalamo-pituitary-gonadal (HPG) axis were determined and elevated expression of esr1, ar, and cyp19a2 (genes involved in sex steroid signaling) in thebrain at the onset of puberty, and in females slightly in advance of the elevation in the expression ofkiss1r.