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Ana Natriashvili
Researcher at University of Freiburg
Publications - 4
Citations - 47
Ana Natriashvili is an academic researcher from University of Freiburg. The author has contributed to research in topics: Signal recognition particle & SecYEG Translocon. The author has an hindex of 2, co-authored 3 publications receiving 16 citations.
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Journal ArticleDOI
The Dynamic SecYEG Translocon.
TL;DR: In this paper, the authors summarize the current knowledge about SecYEG-mediated protein transport, primarily in the model organism Escherichia coli, and describe the dynamic interaction of the SecYeg translocon with its multiple partner proteins.
Journal ArticleDOI
Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle.
Ruth Steinberg,Andrea Origi,Ana Natriashvili,Pinku Sarmah,Mariya Licheva,Princess M. Walker,Claudine Kraft,Stephen High,Joen Luirink,Wei Shi,Martin Helmstädter,Maximilian H. Ulbrich,Hans-Georg Koch +12 more
TL;DR: The study revealed that in Escherichia coli, the 27-amino-acid-long model protein YohP engages an unique SRP-dependent posttranslational insertion pathway that is likely preceded by an mRNA targeting step, which further highlights the enormous plasticity of bacterial protein transport machineries.
Journal ArticleDOI
SecY-mediated quality control prevents the translocation of non-gated porins
Sebastian Jung,Verian Bader,Ana Natriashvili,Hans-Georg Koch,Konstanze F. Winklhofer,Jörg Tatzelt +5 more
TL;DR: This study identified a SecY-mediated quality control pathway to restrict transport of outer membrane porin proteins with a deregulated channel activity into the periplasm by reducing the proof-reading capacity of SecY by introducing the PrlA4 substitutions.
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Exploring protein-dependent changes of the properties of bio-membranes using time-resolved fluorescence
TL;DR: In this paper , the authors proposed a more elegant approach that considers time-resolved fluorescence measurements using inner-membrane vesicles (INV) as an in vitro model without prior protein purification.