Ana Silva

TL;DR: This paper presents the concept and most of the research undertaken all over the world for the development of a bio‐artificial pancreas (BAP) device over the last 30 years.

TL;DR: A system for vascular hollow fiber bio-artificial pancreas development, optimization and in vitro testing was implemented and operated in a simple and fully described manner, allowing other researchers to test a variety of experimental conditions.

TL;DR: In this paper, a condition-based maintenance model, based on Petri nets, is used to analyse the influence of alternative maintenance strategies on the overall degradation of natural stone claddings, and a simplified multi-criteria analysis is carried out to evaluate the economic impact of each maintenance strategy in comparison with the increased durability achieved through its adoption.

TL;DR: A bi-enzymatic micro-analytical bioreactor integrated in a FIA system for glucose measurements is described, which has excellent shelf life, and a very high operational stability that was demonstrated through extensive usage for glucose determinations over 1 year period during which the column retained almost all of its activity.

TL;DR: The use of Petri Nets shows to be more accurate than a more traditional approach based on Markov Chains, but also allows developing future research to consider different environmental conditions, maintenance actions or inspections, amongst other aspects of life-cycle analysis of existing assets.