Andrea Affuso

TL;DR: This paper is the result of an international initiative and is a first attempt to develop guidelines for the care and welfare of cephalopods following the inclusion of this Class of ∼700 known living invertebrate species in Directive 2010/63/EU.

TL;DR: The purpose of this article is to review the existing literature on anesthetic protocols adopted in mice for molecular imaging studies and to report the experience.

TL;DR: The experiments reported here analyze the expression of the transcription factors Titf1, Hhex, Pax8, and Foxe1 in the thyroid primordium of null mutants of each of them and provide the first evidence of gene expression programs, controlled by a hierarchy of transcription factors expressed inThe thyroid presumptive gut domain and directing the progression of thyroid morphogenesis.

TL;DR: It is demonstrated that this neutralizing RNA-aptamer is a promising bio-molecule that can be developed as a more effective alternative to the repertoire of already existing EGFR-inhibitors.

TL;DR: The generated and characterized a selective RNA-based aptamer, GL21.T, that binds the extracellular domain of Axl at high affinity and inhibits its catalytic activity and represents a promising therapeutic molecule for Axl-dependent cancers whose importance is highlighted by the paucity of availableAxl-specific inhibitory molecules.