Andreas Reichenbach

TL;DR: A proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/protective-and prevent the destructive-mechanisms of gliosis.

TL;DR: The two-way communication between Müller cells and retinal neurons indicates that Müllers cells play an active role in retinal function.

TL;DR: In Bergmann glia, astrocytic cells of the cerebellum, this paper identified subcellular compartments termed "glial microdomains", which have a complex surface consisting of thin membrane sheets, contain few mitochondria and wrap around synapses.

TL;DR: An overview of the neuroprotective and detrimental effects of Müller cell gliosis is provided, with accounts on the cellular signal transduction mechanisms and factors which are implicated in Müllercell-mediated neuroprotection, immunomodulation, regulation of Müllers cell proliferation, upregulation of intermediate filaments, glial scar formation, and the generation of neural progenitor/stem cells.

TL;DR: This review gives a survey of recently discoved new functions of Müller cells, living optical fibers that guide light through the inner retinal tissue that enhance the signal/noise ratio by minimizing intraretinal light scattering and conserve the spatial distribution of light patterns in the propagating image.