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Andreas Wicki
Researcher at University of Basel
Publications - 28
Citations - 2018
Andreas Wicki is an academic researcher from University of Basel. The author has contributed to research in topics: Cancer & Urban climate. The author has an hindex of 17, co-authored 28 publications receiving 1851 citations. Previous affiliations of Andreas Wicki include University Hospital of Basel.
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Journal ArticleDOI
Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
Andreas Wicki,François Lehembre,Nikolaus Wick,Brigitte Hantusch,Dontscho Kerjaschki,Gerhard Christofori +5 more
TL;DR: Results indicate that podoplanin promotes tumor cell invasion in vitro and in vivo and induces collective cell migration by filopodia formation via the downregulation of the activities of small Rho family GTPases.
Journal ArticleDOI
The potential role of podoplanin in tumour invasion
TL;DR: This work revisits the mechanism of podoplanin-mediated tumour invasion and compares molecular pathways leading to single and collective cell invasion, and discusses novel distinct concepts of tumour cell invasion.
Journal ArticleDOI
NCAM‐induced focal adhesion assembly: a functional switch upon loss of E‐cadherin
François Lehembre,Mahmut Yilmaz,Andreas Wicki,Tibor Schomber,Karin Strittmatter,Dominik Ziegler,Angelika Kren,Phillip Went,Patrick W. B. Derksen,Anton Berns,Jos Jonkers,Gerhard Christofori +11 more
TL;DR: A mechanistic link is established between the loss of E‐cadherin expression, NCAM function, focal adhesion assembly and cell migration and invasion in EMT.
Journal Article
[Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting.
Damian Wild,Martin Béhé,Andreas Wicki,Daniel Storch,Beatrice Waser,Martin Gotthardt,Boris Keil,Gerhard Christofori,Jean Claude Reubi,Helmut R. Mäcke +9 more
TL;DR: The high density of GLP-1 receptors in insulinomas as well as the high specific uptake of [Lys(40)(Ahx-DTPA-(111)In)NH(2)]exendin-4 in the tumor of Rip1Tag2 mice indicate that targeting of GLp-1 receptor in insulinoma may become a useful imaging method to localize insulinomas in patients, either preoperatively or intraoperatively.
Promising Ligand for Glucagon-like Peptide-1 (GLP-1) Receptor Targeting
Damian Wild,Andreas Wicki,Daniel Storch,Beatrice Waser,Martin Gotthardt,Boris Keil,Gerhard Christofori,Jean Claude Reubi +7 more
TL;DR: In this article, a newly designed exendin-4-DTPA conjugate was used for GLP-1 receptor targeting in human insulinomas and gastrinomas using receptor-avid radioligands.