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Andrés R. Alcántara
Researcher at Complutense University of Madrid
Publications - 133
Citations - 4272
Andrés R. Alcántara is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Lipase & Catalysis. The author has an hindex of 28, co-authored 122 publications receiving 3205 citations. Previous affiliations of Andrés R. Alcántara include University of Córdoba (Spain).
Papers
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Journal ArticleDOI
2‐Methyltetrahydrofuran (2‐MeTHF): A Biomass‐Derived Solvent with Broad Application in Organic Chemistry
Vittorio Pace,Vittorio Pace,Pilar Hoyos,Laura Castoldi,Pablo Domínguez de María,Andrés R. Alcántara +5 more
TL;DR: The properties of 2-MeTHF, the state-of-the-art of its use in synthesis, and several outstanding examples of its application from both industry and academia are described.
Journal ArticleDOI
Immobilization of lipases on hydrophobic supports: immobilization mechanism, advantages, problems, and solutions.
Rafael C. Rodrigues,Jose J. Virgen-Ortíz,José C. S. dos Santos,Ángel Berenguer-Murcia,Andrés R. Alcántara,Oveimar Barbosa,Claudia Ortiz,Roberto Fernandez-Lafuente +7 more
TL;DR: These immobilized lipases may be subject to unfolding and refolding strategies to reactivate inactivated enzymes, and these biocatalysts have been used in new strategies for enzyme coimmobilization, where the most stable enzyme could be reutilized after desorption of the least stable one after its inactivation.
Journal ArticleDOI
Understanding Candida rugosa lipases: an overview.
TL;DR: In the present paper the recent developments published in the CRL field are overviewed, focusing on comparison of structural and biochemical data among isoenzymes (Lip1-Lip5), and their influence in the biocatalytical performance.
Journal ArticleDOI
Biocatalytic Strategies for the Asymmetric Synthesis of α-Hydroxy Ketones
Pilar Hoyos,Josep-Vicent Sinisterra,Francesco Molinari,Andrés R. Alcántara,Pablo Domínguez de María +4 more
TL;DR: The field represents an illustrative example of how biocatalysis can assist practical synthetic processes, and how problems derived from the integration of natural tools in synthetic pathways can be efficiently tackled to afford high yields and enantioselectivities.
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Industrial biotransformations in the synthesis of building blocks leading to enantiopure drugs
TL;DR: This review is focused on describing several industrial processes based on the use of hydrolases and oxido-reductases for obtaining chiral compounds useful for the pharmaceutical industry.