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Andrew J. Molyneux
Researcher at University of Oxford
Publications - 126
Citations - 17316
Andrew J. Molyneux is an academic researcher from University of Oxford. The author has contributed to research in topics: Aneurysm & International Subarachnoid Aneurysm Trial. The author has an hindex of 51, co-authored 121 publications receiving 15406 citations. Previous affiliations of Andrew J. Molyneux include Frenchay Hospital & John Radcliffe Hospital.
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International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms : a randomised trial
TL;DR: In patients with a ruptured intracranial aneurysm, for which endov vascular coiling and neurosurgical clipping are therapeutic options, the outcome in terms of survival free of disability at 1 year is significantly better with endovascular coiling.
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International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion
Andrew J. Molyneux,Richard S. C. Kerr,Ly-Mee Yu,Mike Clarke,Mary Sneade,Julia A. Yarnold,Peter Sandercock +6 more
TL;DR: In patients with ruptured intracranial aneurysms suitable for both treatments, endovascular coiling is more likely to result in independent survival at 1 year than neurosurgical clipping; the survival benefit continues for at least 7 years.
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International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomized trial.
Andrew J. Molyneux,Richard S. C. Kerr,Irene M Stratton,Peter Sandercock,Mike Clarke,Julia A Shrimpton,Rury R. Holman +6 more
TL;DR: In patients with a ruptured intracranial aneurysm, for which endovascular coiling and neurosurgical clipping are therapeutic options, the outcome in terms of survival free of disability at 1 year is significantly better with endov vascular coiling.
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Risk of recurrent subarachnoid haemorrhage, death, or dependence and standardised mortality ratios after clipping or coiling of an intracranial aneurysm in the International Subarachnoid Aneurysm Trial (ISAT): long-term follow-up
Andrew J. Molyneux,Richard S. C. Kerr,Jacqueline Birks,Najib Ramzi,Julia A. Yarnold,Mary Sneade,Joan Rischmiller +6 more
TL;DR: There was an increased risk of recurrent bleeding from a coiled aneurysm compared with a clipped aneurYSm, but the risks were small and the risk of death at 5 years was significantly lower in the coiled group than it was in the clipped group.
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