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Anette Gundersen
Researcher at Scripps Research Institute
Publications - 2
Citations - 130
Anette Gundersen is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Arenavirus & Viral entry. The author has an hindex of 2, co-authored 2 publications receiving 120 citations.
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Journal ArticleDOI
Unique Small Molecule Entry Inhibitors of Hemorrhagic Fever Arenaviruses
Andrew M. Lee,Jillian M. Rojek,Christina F. Spiropoulou,Anette Gundersen,Wei Jin,Alex Shaginian,Joanne York,Jack H. Nunberg,Dale L. Boger,Michael B. A. Oldstone,Stefan Kunz,Stefan Kunz +11 more
TL;DR: High throughput screening of synthetic combinatorial small molecule libraries is used to identify inhibitors of arenavirus infection using pseudotyped virion particles bearing the glycoproteins of highly pathogenic arenaviruses, resulting in the discovery of a series of novel small molecule inhibitors of viral entry.
Journal ArticleDOI
Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers.
Andrew M. Lee,Jillian M. Rojek,Anette Gundersen,Ute Ströher,Ute Ströher,Jean-Marc Juteau,Andrew Vaillant,Stefan Kunz +7 more
TL;DR: These findings indicate that amphipathic DNA polymers (APs) are potent inhibitors of infection with a series of LCMV isolates with IC(50) in the low nanomolar range and provide evidence that APs disrupt the interaction betweenLCMVGP and its cellular receptor, alpha-dystroglycan.