Angelica Varesi

TL;DR: The role of gut microbiota homeostasis in brain health and disease is summarized, evidence for its dysregulation in AD patients is presented, and the potential of prebiotics, probiotics, fecal microbiota transplantation, and diets as complementary therapeutic interventions on disease pathogenesis and progression are examined.

TL;DR: The role of enzymes, mitochondria-targeting compounds, vitamins, carotenoids, organosulfur compounds, nitrogen non-protein molecules, minerals, flavonoids, and non-flavonoids are reviewed and discussed as antioxidant compounds with an anti-aging potential, therefore offering insights into innovative lifespan-extending approaches.

TL;DR: The role of proteins, lipids, metabolites, oxidative-stress-related molecules, and cytokines as possible disease biomarkers are discussed, and the potential of the emerging miRNAs and long non-coding RNAs as diagnostic tools are highlighted.

TL;DR: Evidence for GM alterations and leaky gut in PD patients is presented, the potential of GM-based signatures to serve as disease biomarkers are reviewed, and the emerging role of probiotics, prebiotics, antibiotics, dietary interventions, and fecal microbiota transplantation as supportive therapeutic approaches in PD are highlighted.

TL;DR: In this paper , a comprehensive review of high altitude sickness, including its epidemiology, pathophysiology, and treatments is provided, with a deeper understanding of the pathogenesis of high-altitude diseases, as well as a reasoned approach to environmental or physical factors.