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Angelika K. Sawicka

Researcher at University of Gdańsk

Publications -  11
Citations -  140

Angelika K. Sawicka is an academic researcher from University of Gdańsk. The author has contributed to research in topics: Carnitine & Internal medicine. The author has an hindex of 5, co-authored 8 publications receiving 78 citations.

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L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women.

TL;DR: It is demonstrated that although oral L-carnitine supplementation significantly increased plasma TMAO concentration, no lipid profile changes or other markers of adverse cardiovascular events were detected in healthy aged women over the period of 24 weeks.
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A Pilot Study on the Effects of l-Carnitine and Trimethylamine-N-Oxide on Platelet Mitochondrial DNA Methylation and CVD Biomarkers in Aged Women.

TL;DR: Evidence supports the hypothesis that the correlation between l-carnitine, TMAO and atherosclerosis might be more complex than already postulated, and the alteration of mitochondrial DNA methylation in platelets could be involved in the pathogenesis of this multifactorial disease.
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l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function

TL;DR: Substantial changes in skeletal muscle strength, body mass and composition, as well as knee extensor and flexor muscle strength and serum inflammatory markers in healthy women over 65 years of age were noted.
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Increased Trimethylamine N-Oxide Is Not Associated with Oxidative Stress Markers in Healthy Aged Women.

TL;DR: The results in healthy aged women indicated no relation between TMAO and any determined marker of oxidative stress over the period of 24 weeks, and plasma GBB levels were not affected by L-carnitine supplementation.
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Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women.

TL;DR: The results of this study demonstrate no adverse effects of elevated plasma TMAO, induced by L-carnitine, on the measured parameters at 4 and 12 months after withdrawal of supplementation.