A
Angelika K. Teresky
Researcher at Princeton University
Publications - 13
Citations - 2020
Angelika K. Teresky is an academic researcher from Princeton University. The author has contributed to research in topics: Embryoid body & Cell culture. The author has an hindex of 12, co-authored 13 publications receiving 1914 citations. Previous affiliations of Angelika K. Teresky include Rockefeller University.
Papers
More filters
Journal ArticleDOI
Gain of function mutations in p53.
Dirk P. Dittmer,Sibani Pati,Gerard P. Zambetti,Shelley Chu,Angelika K. Teresky,M Moore,Cathy A. Finlay,Arnold J. Levine +7 more
TL;DR: These data demonstrate a gain of function associated with p53 mutations in addition to the loss of function shown previously to be associated with mutations in this tumour suppressor gene.
Journal ArticleDOI
The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways
Zhaohui Feng,Wenwei Hu,Elisa de Stanchina,Angelika K. Teresky,Shengkan Jin,Scott W. Lowe,Arnold J. Levine +6 more
TL;DR: This study explores four p53-regulated gene products, the beta1 and beta2 subunits of the AMPK, which are shown for the first time to be regulated by the p53 protein, TSC2, PTEN, and IGF-BP3, each of which negatively regulates the IGF-1-AKT-mTOR pathways after stress.
Journal ArticleDOI
Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations
Zhaohui Feng,Wenwei Hu,Angelika K. Teresky,Eva Hernando,Carlos Cordon-Cardo,Arnold J. Levine +5 more
TL;DR: An enhanced fixation of mutations in older individuals is suggested because of the declining fidelity of p53-mediated apoptosis or senescence in response to stress, and a plausible explanation for the correlation between tumorigenesis and the aging process is suggested.
Journal ArticleDOI
Deoxyribonucleic acid replication in simian virus 40-infected cells. II. Detection and characterization of simian virus 40 pseudovirions.
TL;DR: Pseudovirions are enriched, relative to true virions, on the lighter density side of infectious SV40 virus banded to equilibrium in a CsCl gradient.
Journal ArticleDOI
Morphological criteria for the in vitro differentiation of embryoid bodies produced by a transplantable teratoma of mice
TL;DR: Scanning and transmission electron microscopy have been employed to show that the endodermal cells of embryoid bodies, like those of the mouse embryo, are on the outer surface and have highly convoluted surfaces containing numerous microvilli‐like projections.