Anna Cancarini

TL;DR: Analysis of vitreous humor obtained from diabetic patients has made it possible to identify some of the mediators responsible for DR pathogenesis, and the main Vitreous-related factors triggering the occurrence of retinal complication in diabetes are highlighted.

TL;DR: Anti-inflammatory compounds such as intravitreal glucocorticoids, topical non-steroidal anti-inflammatory drugs (NSAIDs), antioxidants, inflammatory molecule inhibitors, renin-angiotensin system (RAS) blockers and natural anti- inflammatory therapies may all be considered to reduce the rate of administration of antineovascularization agents in the treatment of DR.

TL;DR: How studying the biological activity of the vitreous in different in vitro, ex vivo, and in vivo experimental models can provide insights into the pathogenesis of diabetic retinopathy is discussed.

TL;DR: The nomogram could help in ranking the type 2 diabetic patients at higher risk to develop DR and thus with a need for more frequent ophthalmologic checks, without enhancing neither the time nor the costs.

TL;DR: In this large group of hypertensive patients and normotensive individuals, 24-hour systolic BP seems to be the strongest determinant of increased WLR of retinal arterioles.