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Anna Grimaldi
Researcher at Seconda Università degli Studi di Napoli
Publications - 50
Citations - 1551
Anna Grimaldi is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 21, co-authored 45 publications receiving 1085 citations.
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Journal ArticleDOI
Mitochondria as playmakers of apoptosis, autophagy and senescence.
Marianna Abate,Agostino Festa,Michela Falco,Angela Lombardi,Amalia Luce,Anna Grimaldi,Silvia Zappavigna,Pasquale Sperlongano,Carlo Irace,Michele Caraglia,Gabriella Misso +10 more
TL;DR: This work focuses on the mitochondrial commitment to the onset, maintenance and counteraction of apoptosis, autophagy and senescence in the bioenergetic reprogramming of cancer cells.
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Anti-Inflammatory Drugs as Anticancer Agents
Silvia Zappavigna,Alessia Maria Cossu,Anna Grimaldi,Marco Bocchetti,Giuseppe A. Ferraro,Giovanni Francesco Nicoletti,Rosanna Filosa,Michele Caraglia +7 more
TL;DR: This review focuses on the link between inflammation and cancer by describing the anti-inflammatory agents used in cancer therapy, and their mechanisms of action, emphasizing the use of novel anti- inflammatory agents with significant anticancer activity.
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In vivo activity of MiR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma
Maria Teresa Di Martino,Virginia Campani,Gabriella Misso,Maria Eugenia Gallo Cantafio,Annamaria Gullà,Umberto Foresta,Pietro Hiram Guzzi,Maria Castellano,Anna Grimaldi,Vincenzo Gigantino,Renato Franco,Sara Lusa,Mario Cannataro,Pierosandro Tagliaferri,Giuseppe De Rosa,Pierfrancesco Tassone,Pierfrancesco Tassone,Michele Caraglia,Michele Caraglia +18 more
TL;DR: Evidence is provided that SNALPs miR-34a may represent a promising tool for miRNA-therapeutics in MM and analysis of miR -34a and NOTCH1 expression in tumor retrieved from animal demonstrated efficient delivery and gene modulation induced by SNALP- 34a in the absence of systemic toxicity.
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5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress
Monica Lamberti,Stefania Porto,Monica Marra,Silvia Zappavigna,Anna Grimaldi,Daniela Feola,Delia Pesce,Silvio Naviglio,Annamaria Spina,Nicola Sannolo,Michele Caraglia +10 more
TL;DR: The results suggest that cardiotoxic mechanism of chemotherapy agents are different and this disclose a new scenario for prevention of this complication.
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CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells.
Caterina Ieranò,Sandro Santagata,Maria Napolitano,Francesca Guardia,Anna Grimaldi,E Antignani,G. Botti,Claudia Consales,Anna Maria Riccio,Merlin Nanayakkara,Maria Vittoria Barone,Michele Caraglia,Stefania Scala +12 more
TL;DR: The entire axis CXCR4–CXCL12–C XCR7 regulates mTOR signaling in renal cancer cells offering new therapeutic opportunities and targets to overcome resistance to mTOR inhibitors.