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Pierosandro Tagliaferri
Researcher at Magna Græcia University
Publications - 329
Citations - 11512
Pierosandro Tagliaferri is an academic researcher from Magna Græcia University. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 57, co-authored 304 publications receiving 10002 citations. Previous affiliations of Pierosandro Tagliaferri include University of Siena & National Institutes of Health.
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Journal ArticleDOI
Mir-34: A New Weapon Against Cancer?
Gabriella Misso,Maria Teresa Di Martino,Giuseppe De Rosa,Ammad Ahmad Farooqi,Angela Lombardi,Virginia Campani,Mayra Rachele Zarone,Annamaria Gullà,Pierosandro Tagliaferri,Pierfrancesco Tassone,Pierfrancesco Tassone,Michele Caraglia,Michele Caraglia +12 more
TL;DR: Given the broad anti-oncogenic activity of miR-34a, the replacement of oncosuppressor miRNAs provides an effective strategy against tumor heterogeneity and the selective RNA-based delivery systems seems to be an excellent platform for a safe and effective targeting of the tumor.
Journal ArticleDOI
BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells
Pierfrancesco Tassone,Pierfrancesco Tassone,Pierosandro Tagliaferri,Alessia Perricelli,Simona Blotta,Barbara Quaresima,Marialuisa Martelli,Ajay Goel,Vito Barbieri,Francesco Costanzo,Clement Richard Boland,Salvatore Venuta +11 more
TL;DR: The findings suggest a specific chemosensitivity profile of BRCA1-defective cells in vitro, which is dependent on B RCA1 protein expression, and suggest prospective preclinical and clinical investigation for the development of tailored therapeutical approaches in this setting.
Journal ArticleDOI
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches.
Nicola Amodio,Lavinia Raimondi,Giada Juli,Maria Angelica Stamato,Daniele Caracciolo,Pierosandro Tagliaferri,Pierfrancesco Tassone +6 more
TL;DR: The emerging insights on lncRNA expression and functional role in cancer are summarized, focusing on the evolutionary conserved and abundantly expressed metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) that currently represents the best characterized lncRNAs.
Journal ArticleDOI
Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence
Maria Teresa Di Martino,Emanuela Leone,Nicola Amodio,Umberto Foresta,Marta Lionetti,Maria Rita Pitari,Maria Eugenia Gallo Cantafio,Annamaria Gulla,Francesco Conforti,Eugenio Morelli,Vera Tomaino,Marco Rossi,Massimo Negrini,Manlio Ferrarini,Michele Caraglia,Masood A. Shammas,Nikhil C. Munshi,Kenneth C. Anderson,Antonino Neri,Pierosandro Tagliaferri,Pierfrancesco Tassone +20 more
TL;DR: The findings provide a proof-of-principle that formulated synthetic miR-34a has therapeutic activity in preclinical models and support a framework for development of miR -34a–based treatment strategies in MM patients.
Journal ArticleDOI
Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy.
Pierpaolo Correale,Maria Saveria Rotundo,Maria Teresa Del Vecchio,Cinzia Remondo,Cristina Migali,Chiara Ginanneschi,Kwong Y. Tsang,Antonella Licchetta,Susanna Mannucci,Lucia Loiacono,Pierfrancesco Tassone,Guido Francini,Pierosandro Tagliaferri +12 more
TL;DR: The results suggest that a higher FoxP3+ T-lymphocyte tumor infiltration score is a favorable prognostic factor in colon cancer patients undergoing chemo or chemoimmunotherapy.