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Anna Lisa Muntoni
Researcher at National Research Council
Publications - 48
Citations - 2918
Anna Lisa Muntoni is an academic researcher from National Research Council. The author has contributed to research in topics: Ventral tegmental area & Dopamine. The author has an hindex of 27, co-authored 43 publications receiving 2634 citations. Previous affiliations of Anna Lisa Muntoni include University of Sassari & University of Cagliari.
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Endocannabinoids Mediate Presynaptic Inhibition of Glutamatergic Transmission in Rat Ventral Tegmental Area Dopamine Neurons through Activation of CB1 Receptors
TL;DR: The results indicate that the two pathways work in a cooperative manner to release endocannabinoids in the VTA, where they play a role as retrograde messengers for DSE via CB1-Rs.
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Mesolimbic Dopaminergic Decline after Cannabinoid Withdrawal
TL;DR: Data indicate that withdrawal from chronic cannabinoid administration is associated with reduced dopaminergic transmission in the limbic system, similar to that observed with other addictive drugs; these changes in neuronal plasticity may play a role in drug craving and relapse into drug addiction.
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Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons.
TL;DR: It is suggested that an enduring form of neuronal adaptation occurs in DA neurons after subchronic cannabinoid intake at a young age, affecting subsequent responses to drugs of abuse.
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Inhibitory Inputs from Rostromedial Tegmental Neurons Regulate Spontaneous Activity of Midbrain Dopamine Cells and Their Responses to Drugs of Abuse
TL;DR: The results further support the role of the RMTg as one of the main inhibitory afferents to DA cells and suggest that cannabinoids and opioids might disinhibit DA neurons by profoundly influencing synaptic responses evoked by R MTg activation.
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Endogenous Fatty Acid Ethanolamides Suppress Nicotine-Induced Activation of Mesolimbic Dopamine Neurons through Nuclear Receptors
Miriam Melis,Giuliano Pillolla,Antonio Luchicchi,Anna Lisa Muntoni,Sevil Yasar,Steven R. Goldberg,Marco Pistis +6 more
TL;DR: Analysis of modulation of nicotine effects by the endocannabinoid system on dopamine neurons in the ventral tegmental area indicates for the first time that the anorexic lipids OEA and PEA possess neuromodulatory properties as endogenous ligands of PPAR-α in the brain and provide a potential new target for the treatment of nicotine addiction.