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Anna Marie Pyle
Researcher at Yale University
Publications - 247
Citations - 17870
Anna Marie Pyle is an academic researcher from Yale University. The author has contributed to research in topics: RNA & Group II intron. The author has an hindex of 68, co-authored 220 publications receiving 15800 citations. Previous affiliations of Anna Marie Pyle include Columbia University & Howard Hughes Medical Institute.
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Mixed-ligand complexes of ruthenium(II): factors governing binding to DNA
Anna Marie Pyle,Jill P. Rehmann,R. Meshoyrer,Challa V. Kumar,Nicholas J. Turro,Jacqueline K. Barton +5 more
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mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
Dong Chul Kang,Rahul V. Gopalkrishnan,Rahul V. Gopalkrishnan,Qingping Wu,Qingping Wu,Eckhard Jankowsky,Anna Marie Pyle,Paul B. Fisher,Paul B. Fisher +8 more
TL;DR: The melanoma differentiation-associated gene-5 (mda-5) as discussed by the authors is a double-stranded RNA-dependent ATPase that contains both a caspase recruitment domain and RNA helicase motifs.
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Translocation and Unwinding Mechanisms of RNA and DNA Helicases
TL;DR: Through structural and single-molecule investigations, researchers are developing coherent models to explain the functions and dynamic motions of helicase enzymes.
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Crystal structure of a self-spliced group II intron.
TL;DR: Structural and functional analogies support the hypothesis that group II introns and the spliceosome share a common ancestor.
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Ribozymes: a distinct class of metalloenzymes
TL;DR: The exploitation of variable metal geometry and reactivity has expanded ribozyme chemistry and has facilitated the application of in vitro selection for the creation of novel ribozymes.