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Anne Barmettler
Researcher at Harvard University
Publications - 15
Citations - 1519
Anne Barmettler is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 3 publications receiving 1482 citations.
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Journal ArticleDOI
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
Xiao Jun Ma,Zuncai Wang,Paula D. Ryan,Steven J. Isakoff,Anne Barmettler,Andrew P. Fuller,Beth Muir,Gayatry Mohapatra,Ranelle C. Salunga,J. Todd Tuggle,Yen Tran,Diem Tran,Ana Tassin,Paul Amon,Wilson Wang,Wei Wang,Edward Enright,Kimberly Stecker,Eden Estepa-Sabal,Barbara L. Smith,Jerry Younger,Ulysses J. Balis,James S. Michaelson,Atul K. Bhan,Karleen Habin,Thomas M. Baer,Joan S. Brugge,Daniel A. Haber,Mark G. Erlander,Dennis C. Sgroi +29 more
TL;DR: An expression signature predictive of disease-free survival was reduced to a two-gene ratio, HOXB13 versus IL17BR, which outperformed existing biomarkers and may be useful for identifying patients appropriate for alternative therapeutic regimens in early-stage breast cancer.
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Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
Gromoslaw A. Smolen,Raffaella Sordella,Beth Muir,Gayatry Mohapatra,Anne Barmettler,Heidi Archibald,Woo J. Kim,Ross A. Okimoto,Daphne W. Bell,Dennis C. Sgroi,James G. Christensen,Jeffrey Settleman,Daniel A. Haber +12 more
TL;DR: It is shown that gastric cancer cells with high-level stable chromosomal amplification of the growth factor receptor MET are extraordinarily susceptible to the selective inhibitor PHA-665752, which may identify a subset of epithelial cancers that are uniquely sensitive to disruption of this pathway.
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Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis.
Gromoslaw A. Smolen,Beth Muir,Gayatry Mohapatra,Anne Barmettler,Woo J. Kim,Miguel Rivera,Sara M. Haserlat,Ross A. Okimoto,Eunice Kwak,Sonika Dahiya,Judy Garber,Daphne W. Bell,Dennis C. Sgroi,Lynda Chin,Chu-Xia Deng,Daniel A. Haber +15 more
TL;DR: The identification of a dominant somatic genetic lesion in the Brca1/Trp53 mouse model suggests that recurrent secondary hits may also exist in BRCA1-initiated human breast cancer.
Journal ArticleDOI
#Oculoplastics
TL;DR: In this paper , the authors analyzed the source and quality of oculoplastics-related content on TikTok, a popular social media platform, and found that physicians were the leading content creators (38.1%), followed by nonophthalmology MDs/DOs and oculoplastic surgeons/ophthalmologists (16.3%).
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Orbital Index: A Novel Comprehensive Quantitative Tool for Prediction of Delayed Enophthalmos in Orbital Floor Fracture Management
Brandon J. De Ruiter,Vikas S. Kotha,Frank D. Lalezar,Marco Swanson,Amit Kumar,Anne Barmettler,Mark A. Prendes,Edward H. Davidson +7 more
TL;DR: The Orbital Index demonstrated high fidelity and interobserver reproducibility and identified a score of four or greater as a surgical threshold and was a reproducible tool to stratify risk for enophthalmos in orbital floor fracture management.