A
Anne Forus
Researcher at University of Oslo
Publications - 50
Citations - 2588
Anne Forus is an academic researcher from University of Oslo. The author has contributed to research in topics: Comparative genomic hybridization & Chromosome 12. The author has an hindex of 27, co-authored 49 publications receiving 2533 citations. Previous affiliations of Anne Forus include Radboud University Nijmegen & Oslo University Hospital.
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Journal ArticleDOI
Structure of the Supernumerary Ring and Giant Rod Chromosomes in Adipose Tissue Tumors
Florence Pedeutour,Anne Forus,Jean Michel Coindre,Jeanne Marie Berner,Guido Nicolò,Jean François Michiels,Philippe Terrier,Dominique Ranchère-Vince,F. Collin,Ola Myklebost,Claude Turc-Carel +10 more
TL;DR: This work extensively investigated the structure and composition of rings and giant rods in a series of 17 WDLPS‐ALP samples and three intra‐ or intermuscular lipomas (IMLP), revealing a unique combination of particular features strikingly related to these tumors.
Journal ArticleDOI
MDM2 Gene Amplification and Transcript Levels in Human Sarcomas: Relationship to TP53 Gene Status
Vivi Ann Flørenes,Gunhild Mari Mælandsmo,Anne Forus,Åshild Andreassen,Ola Myklebost,Øystein Fodstad +5 more
TL;DR: Signs are provided that increased MDM2 expression level, caused by gene amplification or altered regulation of transcription, is involved in tumor progression of some, but not all, sarcoma subtypes.
Journal ArticleDOI
Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma.
Florence Pedeutour,R.F. Suijkerbuijk,Anne Forus,Jose Van Gaal,Willemijn Van De Klundert,Jean-Michel Coindre,Guido Nicolò,F. Collin,Urbain Van Haelst,Karin Huffermann,Claude Turc-Carel +10 more
TL;DR: To begin to fathom the function of the extra abnormal chromosomes, the amplification of genes, including SAS, MDM2, and GADDI53/CHOP, known to be in the region 12q 13–14 were examined and SAS andMDM2 demonstrated constant co‐amplification.
Journal Article
Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2
Anne Forus,Vivi Ann Flørenes,Gunhild Mari Mælandsmo,P. S. Meltzer,Øystein Fodstad,Ola Myklebost +5 more
TL;DR: A panel of 98 human sarcomas of different subtypes was analyzed to characterize the 12q13-14 amplica and determine which of the genes GLI, A2MR, SAS, MDM2, and GADD153 (CHOP) in this region was most consistently amplified.
Journal ArticleDOI
Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas
Anne Forus,Anne Forus,Daniel Olde Weghuis,Dominique Smeets,Øystein Fodstad,Ola Myklebost,Ad Geurts van Kessel +6 more
TL;DR: Using comparative genomic hybridization (CGH), regions of DNA amplification in primary and metastatic osteosarcomas are identified and mapped, indicating that these regions may harbor genes relevant for the development of these tumors.